Rectal Neuroendocrine Tumor With Inferior Vena Cava Tumor Thrombosis Diagnosed With 68Ga-DOTANOC PET/CT

Abstract

A 69-year-old man with a history of back pain, urinary obstruction, and deep vein thrombosis of both lower extremities 4 years earlier was diagnosed with rectal neuroendocrine tumor, grade 2, Ki-67 index 3%. 68Ga-DOTANOC PET/CT images showed a left pelvic mass extended to the lumen of the inferior vena cava with a high affinity for somatostatin receptor. A tubular focus of radiotracer accumulation after the course of inferior vena cava with filling defect was suggestive of tumor thrombus.

Diagnosis of Pulmonary Embolism on 99mTc-Labeled Macroaggregated Albumin Lung Imaging After Hepatic Arterial Injection for Planning of Radioembolization

“…Lung shunt images should also be assessed for pulmonary defects, particularly with high lung shunt fractions, akin to a lung perfusion only (V/Q) scan. Incidental pulmonary embolism and tumor thrombus have been detected on many other nuclear medicine scans, including 68 Ga-PSMA-617 PET/CT, 68 Ga-DOTANOC PET/CT, and 18 F-FDG PET/CT, with incidental pulmonary embolism detection on IV contrast-enhanced PET/CT reported to be 0.32% 2–4 …”

“…Incidental pulmonary embolism and tumor thrombus have been detected on many other nuclear medicine scans, including 68 Ga-PSMA-617 PET/CT, 68 Ga-DOTANOC PET/CT, and 18 F-FDG PET/CT, with incidental pulmonary embolism detection on IV contrast-enhanced PET/CT reported to be 0.32%. [2][3][4] FIGURE 4. Subsequent CT pulmonary angiogram (A) and MRI chest (B) confirmed pulmonary embolism (white arrow) to the left lower lobe pulmonary artery with more peripheral segmental pulmonary arterial extension.…”