Rectal methods of delivery of medical drugs with a protein nature in the therapies of tumor disease

Ukibayev, Jandos; Datkhayev, Ubaidilla; Myrzakozha, Diyas; Frantsev, A. P.; Karlova, Elmira; Nechepurenko, Yelena; Balpanova, Didara; Almabekova, Alma

doi:10.51847/vctflpy

Cited by 7 publications

(4 citation statements)

References 5 publications

(2 reference statements)

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“…Gallbladder cancer (GBC) is the most prevalent malignant tumor of the biliary system worldwide, with broad regional variation [1][2][3][4]. Although the overall incidence is low, it is the most aggressive biliary tract cancer, having a short median survival from the time of diagnosis.…”

Section: Introductionmentioning

confidence: 99%

Immune-Markers in GallBladder Lesions and their Clinico-Diagnostic and Prognostic Significance - An Overview

Agarwal¹,

AlRawaili²,

AlZalbani³

et al. 2023

Int J Pharm Res Allied Sci

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Gallbladder benign diseases are common and usually cured without further consequences. Some benign illnesses increase the chance of cancer development significantly, whereas others resemble malignant disorders. The biomarkers discussed thus far are among the most extensively researched concerning the different diseases of GBC. Patients with gallbladder cancer are usually diagnosed in later stages when conventional treatments are ineffective. The lack of responsiveness of advanced instances of GBC to existing therapies necessitates the identification of novel prognostic and therapeutic approaches. Novel prognostic biomarkers may provide a crucial breakthrough in this area. Despite the available data and years of research, a prognostic marker that is 100% specific and sensitive to GBC is not yet available. A diverse number of molecular markers have been studied for their potential to be prognostic markers in GBC. p53 and HER2 have been studied very extensively and have shown promise. The deregulation and accumulation of the molecular markers we have discussed so far impact carcinogenesis of the gall bladder. Further analytical studies on the concentration levels of these markers in normal vs precancerous vs cancerous tissues should be carried out. Highly specific prognostic markers can help individualize treatment options to bring down the mortality rate in GBC.

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Section: Introductionmentioning

confidence: 99%

Immune-Markers in GallBladder Lesions and their Clinico-Diagnostic and Prognostic Significance - An Overview

Agarwal¹,

AlRawaili²,

AlZalbani³

et al. 2023

Int J Pharm Res Allied Sci

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“…Benign and malignant cardiac tumors, myxoma, and various non-neoplastic lesions are among the clinical differential diagnoses for intracardiac masses (1,2,3,4). Circulatory tumors are a highly unusual complication of the cardiovascular system.…”

Section: Introductionmentioning

confidence: 99%

“…Circulatory tumors are a highly unusual complication of the cardiovascular system. They are often metastatic tumors caused by neoplasms in other organs (2). The incidence of cardiac tumors is between 0.002-0.03% at all ages based on autopsy (3).…”

Section: Introductionmentioning

confidence: 99%

A case report of a heart mass

Moghadam

Namdar

Zadeh

et al. 2022

ijhs

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Introduction: Certain cardiac tumors are asymptomatic and are detected by chance after autopsy. The clinical signs and symptoms of cardiac tumors vary greatly and are determined mainly by the tumor's location and size rather than its histology. Cardiac masses have a broad differential diagnosis, and it is critical to differentiate between neoplastic and non-neoplastic cardiac masses and benign and malignant neoplasms. Surgery is advised in situations of heart failure symptoms, treatment-resistant ventricular arrhythmias, or blockage of the heart's inlet or outlet pathways. Presentation: In this research, a 60-year-old man presented to the hospital with complaints of shortness of breath, and after an echocardiogram and CT scan, he was diagnosed with a right atrial tumor, which required surgery. Conclusion: The patient was sent to the oncology unit for additional treatment after surgery, excision of the mass, and analysis of the pathology sample.

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“…The liver is one of the most injured organs in blunt trauma, representing 5% of all trauma admissions [1,2]. As the liver is large, it is more prone to both blunt and penetrative trauma.…”

Section: Introductionmentioning

confidence: 99%

An Overview on Liver Trauma Diagnostic & Management Approach, Literature Review.

Alhazmi¹,

Binmahri²,

Maqulah³

et al. 2021

Pharmacophore

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Rectal methods of delivery of medical drugs with a protein nature in the therapies of tumor disease

Cited by 7 publications

References 5 publications

Immune-Markers in GallBladder Lesions and their Clinico-Diagnostic and Prognostic Significance - An Overview

Immune-Markers in GallBladder Lesions and their Clinico-Diagnostic and Prognostic Significance - An Overview

A case report of a heart mass

An Overview on Liver Trauma Diagnostic & Management Approach, Literature Review.

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