Rectal Diazepam Gel in the Home Management of Seizures in Children

Pre-hospital care after a seizure: Evidence base and United Kingdom management guidelines

“…10,11 16 further articles/sources which were considered relevant by the authors but not captured by the original search were also included. 4,[7][8][9][12][13][14][15][16][17][18][19][20][21]38,40 Articles referenced but not captured within the original search were used to complement the review and included those which highlight the scale of the problem, 4,7-9 papers which do not relate directly to pre-hospital services 10,[13][14][15][16][17][18]38,40 or seizure management itself 11,19,20 and one article on simple febrile seizures. 21 There is an extensive literature on the management of the seizure patient after arrival in the ED, however, this is beyond the scope of this review.…”

Intranasal Delivery of Two Benzodiazepines, Midazolam and Diazepam, by a Microemulsion System

“…However, diazepam via intravenous and rectal routes have several drawbacks [5][6][7][8]: 1) The establishment of an intravenous access is not practical in an emergency situation when the patient is not in a hospital. A highly qualified, trained medical person is required for this procedure; 2) The use of rectal diazepam results in variable plasma levels and fails to terminate 30% of seizures [9].…”

The knowledge, attitudes and behaviors of parents for the non-hospital management of seizures who have children with recurrent seizures

“…Rektal diazepem nöbet kontrolünde sık kullanıl-maktadır. Hastane dışında kullanımının güvenli ve etkili olduğu bildirilmektedir (14)(15)(16) . Çalışmamızda, ebeveynlerin yarısından fazlasının bilgilendirilmelerine rağmen, rektal ilaç uygulamasına sıcak bakmadı-ğı görülmekle birlikte, bu oran yurt dışında yapılan bir çalışmada, %19 olarak belirtilmiştir (14) .…”