Reconstruction of the Flexor Tendon Sheath

Oei, T. S.; Pj, Klopper; Spaas, J. A. J.; Buma, P.

doi:10.1016/s0266-7681(96)80017-9

Cited by 16 publications

(9 citation statements)

References 28 publications

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“…For example, surgical sutures, tendon sheath damage, and postoperative immobilization all contribute to adhesion formation [5]. Although efforts have been made to find ways to prevent and lessen tendon adhesion, such as a better suture technique for the tendon sheath, the enhancement of local blood supply, and the local application of chondroitin sulfate, collagen protein and detran-70, the benefits have not been entirely satisfactory [6,7]. SY was extracted from the flower of safflower plant, Carthamus tinctorius L. (Compositae), which had been extensively used in traditional Chinese medicine for the treatment of cardio-cerebrovascular diseases.…”

Section: Introductionmentioning

confidence: 99%

An Experimental Study on the Effect of Safflower Yellow on Tendon Injury-Repair in Chickens

Liu¹,

Luo²,

Ouyang³

et al. 2011

Journal of Surgical Research

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Section: Introductionmentioning

confidence: 99%

An Experimental Study on the Effect of Safflower Yellow on Tendon Injury-Repair in Chickens

Liu¹,

Luo²,

Ouyang³

et al. 2011

Journal of Surgical Research

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“…First of all, the CX‐CAM film constitutes of collagens and GAG, which act as a dense barrier against cell recruitment during the inflammatory phase, largely responsible for adhesions. Similar barrier effects have been observed in collagen based barriers . Second, decellularized cartilage ECM may have further deterred adhesion and angiogenesis from peritendinous areas via inherent antiangiogenic and antiadhesive molecules .…”

Section: Discussion and Conclusionmentioning

confidence: 70%

Cross‐linked cartilage acellular matrix film decreases postsurgical peritendinous adhesions

et al. 2019

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Cartilage extracellular matrix contains antiadhesive and antiangiogenic molecules such as chondromodulin‐1, thrombospondin‐1, and endostatin. We have aimed to develop a cross‐linked cartilage acellular matrix (CAM) barrier for peritendinous adhesion prevention. CAM film was fabricated using decellularized porcine cartilage tissue powder and chemical cross‐linking. Biochemical analysis of the film showed retention of collagen and glycosaminoglycans after the fabrication process. Physical characterization of the film showed denser collagen microstructure, increased water contact angle, and higher tensile strength after cross‐linking. The degradation time in vivo was 14 d after cross‐linking. The film extract and film surface showed similar cell proliferation, while inhibiting cell migration and cell adhesion compared to standard media and culture plate, respectively. Application of the film after repair resulted in similar tendon healing and significantly less peritendinous adhesions in a rabbit Achilles tendon injury model compared to repair only group, demonstrated by histology, ultrasonography, and biomechanical testing. In conclusion, the current study developed a CAM film having biological properties of antiadhesion, together with biomechanical properties and degradation profile suitable for prevention of peritendinous adhesions.

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“…Collagen has been largely used in the production of biomaterials and as vehicle for its biocompatibility and minimum immunological response 12 . The use of this abundant source associated with the proper processing of these tissues may represent a significant source of new materials, which may be used in tissue engineering or in regeneration techniques 2,[7][8][9] .…”

Section: Discussionmentioning

confidence: 99%

Porcine peritoneum as source of biocompatible collagen in mice

Jardelino¹,

Takamori²,

Hermida³

et al. 2010

Acta Cir. Bras.

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Purpose:To investigate the biocompatibility and biodegradability of a membrane made from porcine peritoneum. Methods: The membrane (5x5 mm) was inserted in the subcutaneous tissue on the back of 15 mice, which were killed after 1, 3 and 9 weeks (ISO 10993-6). The cellular components of the inflammatory response and degradation of the membrane were analyzed in hematoxylin-eosin-stained histological sections. Results: After one week, mononuclear cells were observed inside the membrane. After three weeks, the material was almost completely absorbed. After nine weeks, there was no presence of material and there were signs of tissue remodeling. There was neither a foreign body reaction nor signs of tissue necrosis. Conclusion: The collagen membrane derived from porcine peritoneum is biocompatible and bioabsorbable when implanted in the subcutaneous tissue of mice. Key words: Materials Testing. Biocompatible Materials. Subcutaneous Tissue. Peritoneum. Mice RESUMO Objetivo: Investigar a biocompatibilidade e biodegradabilidade de uma membrana feita de peritônio suíno. Métodos: A membrana (5x5 mm) foi inserida no tecido subcutâneo dorsal de 15 camundongos, que foram mortos após uma, três e nove semanas (ISO 10993-6). Os componentes celulares da resposta inflamatória e a degradação da membrana foram analisados em cortes corados em hematoxilina-eosina. Resultados: Após uma semana, células mononucleares foram observadas dentro da membrana. Após três semanas, o material foi quase completamente absorvido. Após nove semanas, não houve presença do material e houve sinais de remodelação tecidual. Não houve reação de corpo estranho nem sinais de necrose tecidual. Conclusão: A membrana colágena derivada de peritônio suíno é biocompatível e bioabsorvível quando implantada no tecido subcutâneo do camundongo. Descritores: Teste de Materiais. Materiais Biocompatíveis. Tela Subcutânea. Peritônio. Camundongos.

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Reconstruction of the Flexor Tendon Sheath

Cited by 16 publications

References 28 publications

An Experimental Study on the Effect of Safflower Yellow on Tendon Injury-Repair in Chickens

An Experimental Study on the Effect of Safflower Yellow on Tendon Injury-Repair in Chickens

Cross‐linked cartilage acellular matrix film decreases postsurgical peritendinous adhesions

Porcine peritoneum as source of biocompatible collagen in mice

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