Reconstructing Severe Lower Extremity Skin Necrosis in a Pediatric Patient

Sarrami, Shayan M.; Ferry, Andrew M.; Buchanan, Edward P.; Gerow, Frank T; Koshy, John C.

doi:10.1097/01.asw.0000752716.25014.ca

Cited by 7 publications

(10 citation statements)

References 11 publications

(40 reference statements)

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“…15 Larger superficial defects, however, frequently benefit from the addition of biologic wound agents prior to graft placement. 17 Similar to results seen in the management of patients with third-degree burns, biologics followed by STSG has been shown to greatly decrease scar contracture over time. 18 Defects with exposure of the underlying tendon or bone, on the other hand, require more complex management.…”

Section: Reconstructive Approachmentioning

confidence: 67%

Use of Biologic Agents in Extremity Reconstruction

et al. 2022

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Skin and soft tissue defects of the lower extremity present a unique challenge for the reconstructive surgeon. Successful repair of the lower extremity relies not only on strong anatomical knowledge and surgical expertise, but also on careful consideration of the numerous preoperative factors and indications that may alter the patient's response to operative management. While many of these injuries result from burns, avulsive trauma, diabetes, or vascular insufficiencies, a significant portion can be associated with resection of neoplastic pathologies. This review outlines the uses, indications, and considerations for biologic wound agents in reconstructing skin and soft tissue defects of the lower extremity following Mohs micrographic surgery.

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Section: Reconstructive Approachmentioning

confidence: 67%

Use of Biologic Agents in Extremity Reconstruction

et al. 2022

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“…Since first being used for burn reconstruction, biologic wound agents have been employed to reconstruct defects of the lower extremity, abdominal wall, and face. 6 7 Herein, we discuss the role of said technologies in reconstructing postablative defects of the lips and cheeks in patients following surgical resection of cutaneous malignancies.…”

mentioning

confidence: 99%

“…Since first being used for burn reconstruction, biologic wound agents have been employed to reconstruct defects of the lower extremity, abdominal wall, and face. 6,7 Herein, we discuss the role of said technologies in reconstructing postablative defects of the lips and cheeks in patients following surgical resection of cutaneous malignancies. majority of patients undergoing reconstructive surgery following Mohs micrographic surgery typically have their procedure performed under sedation with long-lasting local anesthetic, as such the concern for life-threatening complications occurring during surgery is low.…”

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confidence: 99%

Use of Biologic Agents for Lip and Cheek Reconstruction

Depani

Thornton

2021

Semin Plast Surg

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The unique requirements of reconstructing cheek defects, often with its proximity to the mobile elements of the face including the lip and the eyelid, have been met very handily with the directed and thoughtful use of biologic wound healing agents. One of the key advantages of these agents is their ability to provide coverage in patients with multiple comorbid conditions for the mobile elements of the cheek where the cervicofacial advancement flap is contraindicated due to its anesthetic requirement. The biologic agents are also highly successful coverage options for patients who have limited skin laxity to provide for proper skin closure using the standard cheek closure techniques with local flaps. In addition, these agents provide an ability to provide stable wound closure with minimal wound care while waiting for the excisional biopsy results to be finalized. This article describes the unique indications for biologic wound agents, including preservation of lip and eyelid mobile element anatomy without retraction from a local flap, which has not been previously described.

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“…42,43 Despite this, there is a paucity of high quality data for many products' off-label uses thereby making it difficult for surgeons to elucidate their efficacy. 44,45 When compared with traditional skin grafting techniques, many biologic wound agents have a steep learning curve which often leads new users to frequently experience complications. 19 Lastly, there is limited data available regarding the impact that biologic wound agents have on health care-related costs.…”

Section: Applicationsmentioning

confidence: 99%

Overview of Biologic Agents Used in Skin and Soft Tissue Reconstruction

et al. 2022

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Wound healing is a highly complex process mediated by cellular interactions at the microscopic level. Increased understanding of wound healing physiology has served as the foundation for translational research to develop biologic wound care technologies that have profoundly affected patient care. As the reader will see throughout this series in Seminars in Plastic Surgery, biologic wound technologies have broad applications and have greatly impacted the reconstructive ladder. Despite their frequent use, many surgeons lack familiarity with the myriad of products available on the market along with each product's relative advantages and shortcomings. This overview will discuss the classification of biologic wound agents used to reconstruct defects of the skin and soft tissue along with the advantages and disadvantages associated with their use.

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Reconstructing Severe Lower Extremity Skin Necrosis in a Pediatric Patient

Cited by 7 publications

References 11 publications

Use of Biologic Agents in Extremity Reconstruction

Use of Biologic Agents in Extremity Reconstruction

Use of Biologic Agents for Lip and Cheek Reconstruction

Overview of Biologic Agents Used in Skin and Soft Tissue Reconstruction

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