Recommendations on Herbs and Herbal Formula in Cancer Prevention

Abstract

Herbs are naturally rich in bioactive herbiceuticals or plant products with food value to keep energy balance in the body and promise substantial therapeutic value in several diseases. Major herbs have specific active ingredient(s) with cancer therapeutic effects. Herbs are now part of nutrition supplements at nonprescription counters and their selfprescription has increased at large scale in hope of cancer prevention. The government agencies monitor and regulate the herbal use in cancer prevention and cancer management with update information of herbal side effects and safety to public. In present paper, different herbs are surveyed in the use of general health with an account of recommended potential herbs in cancer prevention. The biochemical mechanism of cancer prevention in tissues by herbs is proposed. Broadly herbs are rich in alkaloids, flavones, antioxidants, xanthones, omega-3 fatty acids, vitamins, minerals and fibers. Most of the herbs are derived from plants and they act as regulatory biochemical metabolites either by direct intermediary metabolism or regulating cancer pathways and stimulating immunity. The focus of review is to introduce available herbs, herbal biochemical action and herbiceutical anticancer formula. The herbal anticancer formula may be prepared by using: antiproliferative herb extracts combined with vitamin supplement, lactate dehydrogenase enzyme inhibitor, palliative alkalizing sodium or potassium salts as mixture in liquid, paste or syrup form. Herbiceuticals from herbs are potential anticancer supplements if used with care and regulatory guidelines.

The chemosensitizing effect of aqueous extract of sweet fennel on cisplatin treated HeLa cells

“…This augments the aerobic energy metabolism which leads to lactic dehydrogenase (LDH) inhibition and lactate accumulation. LDH plays an active role in development of malignancy as the enzyme LDH generates product NAD+ and two pyruvate molecules from one glucose [20].…”

Effect of Thyme and Rosemary on Liver Functions in Toxicated Rats by Aflatoxins

“…Herbs are normally wealthy in bioactive plant items with nourishment esteem as considerable restorative incentive in a few illnesses ( Sharma, 2010). Thyme (Thymus vulgaris) was having a place with the Lamiacea family a sweet-smelling local herb in the Mediterranean area.…”

Anticancer activity of aqueous myrrh extract alone and in combination with cisplatin in HeLa cells

“…Products extracted from species in the genus Commiphora have significant antibacterial, anti-inflammatory, and antitumor properties [7], in addition to their anti-proliferative effects in lung, pancreas, breast, and prostate cancers [8]. Therefore, this work evaluated the cytotoxic, apoptotic, autophagic, and chemosensitizing potential of the inexpensive medicinal plant, myrrh, alone and in combination with CDDP, on human cervical cancer cells in vitro using a cell proliferation assay, the quantification of DNA fragmentation, and electron microscopy.…”