Recognizing Sepsis as a Global Health Priority — A WHO Resolution

Multi-Omics Research Trends in Sepsis: A Bibliometric, Comparative Analysis Between the United States, the European Union 28 Member States, and China

“…In this context, multi-omics research efforts, which involve more than one ''-omics'' regimes, are more likely to put research results in biological context, compared to studies that involve only one of the ''-omics'' layers that extend from the genome to the phenome. This is of particular interest for sepsis, which has been recognized by the World Health Organization as a global health concern and a priority research area for both funding bodies and commissioned research (Reinhart et al, 2017).…”

Sepsis: who will shoot first? Pharma or diagnostics?

“…Sepsis has finally been acknowledged as a worldwide issue through a World Health Organization resolution in May 2017 [1,2]. This was a year ago, but so far very few things have changed.…”

Sepsis, one of CMAJ’s four new areas of focus

“…Most of these deaths are preventable. 1,4 Describing sepsis as the common pathway to death and disability from most infections is not just cosmetic packaging, but has relevance in its recognition and treatment. Regardless of its cause, the signs and symptoms of sepsis are nonspecific, following a pattern; treatment options are limited (e.g., antimicrobial agents, fluids, oxygen and cardiorespiratory support).…”

“…1 The approach to diagnosis and treatment (simple bundled therapy) can be taught easily to health care workers and offered in both resource-rich and -poor environments. 4 About 25%-30% of people will die during an acute episode of sepsis, with higher rates in low-income countries. 1 Major determinants of death include late diagnoses, poor health-seeking behaviours and lack of access to health care.…”

“…Sepsis is not simply a clinical disease; it is also a social, an economic and a political disease, as indicated by a recent United Nations resolution. 4 The situation in Canada is no different from any other part of the world where inequity in access and quality of care exist. In our large cities, tertiary and quaternary care facilities follow established guidelines and protocols; however, Canada's large land mass and remote communities, in which health care may be suboptimal, render sepsis a critical problem for many Canadians.…”