Recent Trends in Nickel‐Catalyzed C−S Bond Formation

Abstract

Recently, sulphur containing molecules have witnessed significant recognition due to their wide application in various fields. In this regard, the synthesis of such CÀ S containing moieties has become a distinguished and omnipresent research sector in organic chemistry. The transition metal catalysts have been widely utilized in this field for the CÀ S bond formation. Among them, nickel catalysts have attracted great attention owing to their relatively lower toxicity, highly economical, plentiful and efficient metal which come up as a substitute for toxic and expensive 4d and 5d transition metals. The latest advancement in nickelcatalyzed CÀ S bond making reactions are reviewed and covers literature from 2015-2021.

Recent Metal-Catalyzed Methods for Thioether Synthesis

“…Scheme 11 The first nickel-catalyzed C-S coupling. 49 Since then, a moderate number of papers and reviews 50 have been published for nickel-catalyzed C-S cross-couplings. The abundant nickel has become a widely used metal for homogeneous catalysis in general, 51 but much less research was conducted in the field of C-S couplings compared to palladium.…”

Recent Advances in the Nickel‐catalysed Electrochemical Coupling Reactions with a Focus on the Type of Bond Formed

“…In recent years, due to the rising public awareness of environmental concerns, there has been much interest in advancing to increasingly sustainable chemical processes. Cross‐coupling reactions employing transition metals have historically been used extensively as powerful, targeted, and high‐yielding methods in synthetic chemistry [1–6] . Electrochemical metal catalysis has recently drawn substantial attention as an enabling technology for modern synthetic chemistry [7,8] .…”

“…Cross-coupling reactions employing transition metals have historically been used extensively as powerful, targeted, and high-yielding methods in synthetic chemistry. [1][2][3][4][5][6] Electrochemical metal catalysis has recently drawn substantial attention as an enabling technology for modern synthetic chemistry. [7,8] This approach represents an eco-friendly and economically viable method, as the electric current can controllably stimulate the development of reactive intermediates and catalysts, without the use of external oxidizing or reducing agents [9] and it is more selective, produces less trash, and operates under moderate circumstances.…”

Ruthenium‐Catalyzed Direct Reductive Amination of Carbonyl Compounds for the Synthesis of Amines: An Overview

“…[11] Utilizing readily available and ecologically benign reagents, chemical research continues to prioritize the creation of reliable catalytic processes for the selective and economically efficient synthesis of amines. [12][13][14][15][16][17][18][19][20][21][22][23] Since homogeneous catalysts are often dissolved metal complexes, all catalytic sites are readily accessible. Though homogeneous catalysts are often dissolved metal complexes, all catalytic sites are easily accessible, and chemoselectivity, regioselectivity, and enantioselectivity can be modified.…”

“…Although there are some limitations related to work‐up and waste management, the usage of non‐catalytic reagents, such as metal hydrides, is dependable, well‐established, and successful [11] . Utilizing readily available and ecologically benign reagents, chemical research continues to prioritize the creation of reliable catalytic processes for the selective and economically efficient synthesis of amines [12–23] …”