Recent trends in isomeric thienoquinoxalines [1980‐2000]

A Convenient and Efficient Conversion of 4-Aminobenzophenone into Some New 1,2,3-Triazole and Benzothiazole Derivatives

“…A wide variety of benzothiazole and triazole derivatives have been developed as anticancer agents [1][2][3][4][5][6] and flavone (egquercetin) and isoflavone (genistien) isosteres to inhibit PTK enzymes 7 Tricyclazole is a well known fungicide for the control of Piricularia oryzae in the prevention of rice blast 8 furthermore, new 1,3,4-triazole derivatives have been reported as potential anticonvulsants 9 and anti-inflammatory and analgesic agents. 10 Taking all the above benefits into consideration and in continuation of our work on the synthesis of many fused heterocyclic systems [11][12][13][14][15][16][17] we investigate the use of 4-aminobenzophenone for the synthesis of these fused heterocyclic systems with the aim of investigating their antimicrobial activities.…”

4-[2-(Benzylsulfanyl)acetyl]-3,4-dihydroquinoxalin-2(1H)-one

“…For the biological activity of quinoxalines, see: Ali et al (2000); Moustafa & Yameda (2001). For related structures see: Nasir et al (2009).…”

Synthesis of Quinoxaline Azido and Amino Reverse Ribofuranoside and TheirO-Regioisomers

“…[3] The quinoxalines are a class of heterocyclic compounds with different applications in various fields, including pharmacology [4,5] and agricultural chemistry. [6,7] The pharmacological applications of quinoxalines are reported as angiotension II receptor antagonists, [8] N -methyl-D-aspartate (NMDA) antagonists, [9] anti-inflammatory, [10] antidepressanttranquilizing, [11,12] antitumor agents [13,14] as well as agents against hepatitis B virus (HBV). [15] Quinoxaline derivatives have been shown to block selectively EGFR kinase.…”