A Convenient and Efficient Conversion of 4-Aminobenzophenone into Some New 1,2,3-Triazole and Benzothiazole Derivatives

Abstract

Several heterocyclic systems such as 1,2,3‐triazoles (5–9), pyrimidotriazoles (10–13), benzothiazole (16), thiazolo (17), and pyrimidinone derivative (18) was obtained from 4‐aminobenzophenone (1) and the appropriate reagents.

Comprehensive Synthesis of Photoreactive Phenylthiourea Derivatives for the Photoaffinity Labeling

“…Kamel et al. reported that 4‐aminobenzophenone reacts with potassium thiocyanate,(space)forming a PTU derivative . In our preliminary experiments, however, m ‐toluidine did not react under the conditions they used.…”

“…The methodology may afford other information near the binding sites, which cannot obtain from structure‐activity relationship studies. A few studies have elucidated biological activities on the synthesis of azide [6., 7] and benzoyl (benzophenone) attached to the aromatic ring of PTU. However no study on typical photophores with their biological activities has been reported.…”

The impact of 1,2,3-triazoles in the design of functional coatings

“…Moreover, the Cu(I) catalyzed azide-alkyne cycloaddition reaction is regiospecic, chemoselective; thermodynamically and kinetically favourable (50 and 26 kcal mol À1 , respectively). 19 Apart from the azide-alkyne cycloaddition reaction, 1,2,3-triazole compounds can also be synthesized by other routes like diazotization of aromatic orthodiamines, 20 C-H activation of aryl triazine compounds in presence of lead acetate catalyst, 21 reaction of organic azides with ethylacetoacetate 22 in presence of sodium methoxide catalyst etc. (Fig.…”