Recent Trends in Iron‐Catalyzed Reactions towards the Synthesis of Nitrogen‐Containing Heterocycles

Abstract

Heterocycles are generally biologically active compoundsa nd find widespread applications in medicinalc hemistry,a gricultural science and the fine chemical industry.F or the synthesis and functionalization of heterocycles,g reat efforts have been ascribed over the past decades.T he syntheses of heterocyclic compounds are significant due to their diverse biological activity.R ecently,i ron-catalyzed reactions have experienced remarkable progress in the synthesiso fh eterocycles.T hisr eview summarizes recent trends in the iron-catalyzed synthesiso fn itrogen-containingheterocyclic compounds.1I ntroduction

Boehmite@SiO2@ Tris (hydroxymethyl)aminomethane‐Cu(I): a novel, highly efficient and reusable nanocatalyst for the C‐C bond formation and the synthesis of 5‐substituted 1H‐tetrazoles in green media

“…[26] Numerous methods have been developed for the synthesis of tetrazoles, [20,27,28] they have been generally synthesized by [3 + 2]-cycloaddition reaction between nitriles and azides in the presence of various transition metal catalysts, such as Pd, [20,28,29] Ni, [22,30,31] and iron compounds. [32][33][34] Methods for the synthesis of 5-substituted 1H-tetrazoles from aldoximes or aldehydes in the presence of copper (II) catalysts have also been reported. [35] However, some methods have disadvantages such as the need for toxic metals and explosive azide sources.…”

NEW ROUTE FOR THE SYNTHESES OF SOME NOVEL DERIVATIVES OF 3-ARYL BENZO[d] THIAZOLE-2(3H)-IMINE FROM HIGH SUBSTITUTED THIOUREAS

“…It is clear that despite changing R 1 in thioureas, the structure of all final compounds looks quite similar. Comparatively experimental results revealed that the selection of R 1 = CH3, C2H5, CN, NO2 either in para or meta positions led to the same product [R 1…”

“…Fused heterocyclic compounds are the key valuable and structural scaffolds in a broad variety of natural products, drug molecules, and functional materials [1][2][3]. Among them, the analogues of benzothiazole and its derivatives have a significant role due to their wide variety of biological activities and applications in the pharmaceutical industry.…”

Recent Advances in Microwave Assisted Multicomponent Reactions

“…They have wide range of applications and are powerful tools in small molecule synthesis . Even though, Palladium is the most widely used catalyst in transition metal catalysis Ag, Fe, Zn, Cu, Mn, Co, Ni etc… are also efficiently utilised now a days …”