“…Several review papers have been published on mathematics and drug resistance (Agur, 2010; Chapman et al, 2007; Clare et al, 2000; Fister and Panetta, 2000; Foo and Michor, 2010; Gardner, 2002a; Gardner and Fernandes, 2003; Goldie and Coldman, 1998; Kufe et al, 2003; Michelson, 1993; Michor et al, 2006; Panagiotopoulou et al, 2010; Piccart-Gebhart, 2003; Retsky et al, 2005; Simon and Norton, 2006; Swierniak et al, 2009; Wodarz and Komarova, 2005). In view of the present understanding of MDR, it turns out that most of the review papers have focused on a subset of the issues related to drug resistance.…”