Recent progress in nanomaterial-based assay for the detection of phytotoxins in foods

Chen, Qilei; Zhu, Lin; Chen, Jiaxuan; Jiang, Tao; Ye, Huazhen; Ji, Hong; Tsang, Siu-Wai; Zhao, Zhongzhen; Yi, Tao; Chen, Hubiao

doi:10.1016/j.foodchem.2018.10.075

Cited by 30 publications

(10 citation statements)

References 102 publications

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“…Varieties of SPE adsorbing materials can not only be customized according to the target substance, but also can match with different analysis equipment, which meets the detection requirements of high selectivity, high specificity and high throughput [19,20]. And many different nanomaterials have been studied and reported in the preparation of SPE adsorbent [21][22][23]. Among them, magnetic SPE, as a new type of pretreatment process, uses functionalized magnetic materials as adsorbents, and under the action of an external magnetic field, these magnetic adsorbents can be efficiently separated from the matrix samples [24][25][26].…”

Section: Introductionmentioning

confidence: 99%

Synthesis of Magnetic Metal-Organic Frame Material and Its Application in Food Sample Preparation

Yang

Wang

Pan

et al. 2020

Foods

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A variety of contaminants in food is an important aspect affecting food safety. Due to the presence of its trace amounts and the complexity of food matrix, it is very difficult to effectively separate and accurately detect them. The magnetic metal-organic framework (MMOF) composites with different structures and functions provide a new choice for the purification of food matrix and enrichment of trace targets, thus providing a new direction for the development of new technologies in food safety detection with high sensitivity and efficiency. The MOF materials composed of inorganic subunits and organic ligands have the advantages of regular pore structure, large specific surface area and good stability, which have been thoroughly studied in the pretreatment of complex food samples. MMOF materials combined different MOF materials with various magnetic nanoparticles, adding magnetic characteristics to the advantages of MOF materials, which are in terms of material selectivity, biocompatibility, easy operation and repeatability. Combined with solid phase extraction (SPE) technique, MMOF materials have been widely used in the food pretreatment. This article introduced the new preparation strategies of different MMOF materials, systematically summarizes their applications as SPE adsorbents in the pretreatment of food contaminants and analyzes and prospects their future application prospects and development directions.

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Section: Introductionmentioning

confidence: 99%

Synthesis of Magnetic Metal-Organic Frame Material and Its Application in Food Sample Preparation

Yang

Wang

Pan

et al. 2020

Foods

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“…Various sensing systems such as surface plasmon resonance (SPR) biosensors, electrochemical biosensors, fluorescence biosensors, colorimetric assays, competitive enzyme-linked immunosorbent assay (ELISAs) and microfluidic immunoassay have been developed for analysis of toxins from different sources including clinical samples, foods, water and feeds [60][61][62][63][64][65][66]. Among these biosensing systems, electrochemical biosensors and biotransducers are more attractive because they offer several advantages such as high sensitivity, operational simplicity, relatively low cost, easily miniaturization and suitable on-site analysis [8,[11][12][13][14][15][16][17][18][19][67][68][69]. These advantages make electrochemical biosensors/transducers of microbial toxins powerful tools in many areas including food, environmental and medical monitoring, disease diagnosis and anti-terrorism security.…”

Section: Introductionmentioning

confidence: 99%

“…These advantages make electrochemical biosensors/transducers of microbial toxins powerful tools in many areas including food, environmental and medical monitoring, disease diagnosis and anti-terrorism security. Owing to the large surface areas and excellent conductivities, the integration of 2D nanomaterials (e.g., graphene and TMDs) and their nanocomposites with electrochemical transducers has great potential to enhance the analytical performance of electrochemical biosensors for detection of toxins [8,[11][12][13][14][15][16][17][18][19]. For example, since its birth, multiple research initiatives on graphene applied to electroanalytical chemistry have been launched worldwide, and analysts have been developing a plethora of different graphene-based electrochemical sensing platforms for detection of various targets including microbial toxins.…”

Section: Introductionmentioning

confidence: 99%

“…Therefore, the scope of application of 2D nanomaterial-based electrochemical biosensors has been constantly expanding in the field of toxin detection. Some of these studies have been reviewed elsewhere with a focus on the fabrication and toxin detection of graphene-based electrochemical biosensors or as subclassifications in more generalized overviews of the nanomaterial-based electrochemical biosensors [8,[11][12][13][14][15][16][17][18][19]. In this review, we will focus on the recent development of GO/rGO and/or MoS 2 /MoSe 2 -based electrochemical biosensors for the determination of various microbial toxins, such as bacterial toxins, fungal toxins and algal toxins, highlighting some of their current achievements, technical challenges/limitations and the future directions by means of a set of selected recent publications.…”

Section: Introductionmentioning

confidence: 99%

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Two-Dimensional Layered Nanomaterial-Based Electrochemical Biosensors for Detecting Microbial Toxins

Jian

et al. 2019

Toxins

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Toxin detection is an important issue in numerous fields, such as agriculture/food safety, environmental monitoring, and homeland security. During the past two decades, nanotechnology has been extensively used to develop various biosensors for achieving fast, sensitive, selective and on-site analysis of toxins. In particular, the two dimensional layered (2D) nanomaterials (such as graphene and transition metal dichalcogenides (TMDs)) and their nanocomposites have been employed as label and/or biosensing transducers to construct electrochemical biosensors for cost-effective detection of toxins with high sensitivity and specificity. This is because the 2D nanomaterials have good electrical conductivity and a large surface area with plenty of active groups for conjugating 2D nanomaterials with the antibodies and/or aptamers of the targeted toxins. Herein, we summarize recent developments in the application of 2D nanomaterial-based electrochemical biosensors for detecting toxins with a particular focus on microbial toxins including bacterial toxins, fungal toxins and algal toxins. The integration of 2D nanomaterials with some existing antibody/aptamer technologies into electrochemical biosensors has led to an unprecedented impact on improving the assaying performance of microbial toxins, and has shown great promise in public health and environmental protection.

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“…Graphene oxide (GO) is a nanostructured material formed by graphite sheets (graphene) in which some of the aromatic C=C double bonds are oxidized, introducing oxygen atoms and giving rise to different functional groups (epoxides, alcohols, carboxylic acids). Due to the noteworthy importance of graphene and graphene oxide as nanomaterials in various application fields, a very high number of papers regarding their production can be found in the literature along with reviews [1,2,3], to which we refer with respect to syntheses and applications.…”

Section: Introductionmentioning

confidence: 99%

Graphene Oxide: A Smart (Starting) Material for Natural Methylxanthines Adsorption and Detection

et al. 2019

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Natural methylxanthines, caffeine, theophylline and theobromine, are widespread biologically active alkaloids in human nutrition, found mainly in beverages (coffee, tea, cocoa, energy drinks, etc.). Their detection is thus of extreme importance, and many studies are devoted to this topic. During the last decade, graphene oxide (GO) and reduced graphene oxide (RGO) gained popularity as constituents of sensors (chemical, electrochemical and biosensors) for methylxanthines. The main advantages of GO and RGO with respect to graphene are the easiness and cheapness of synthesis, the notable higher solubility in polar solvents (water, among others), and the higher reactivity towards these targets (mainly due to π–π interactions); one of the main disadvantages is the lower electrical conductivity, especially when using them in electrochemical sensors. Nonetheless, their use in sensors is becoming more and more common, with the obtainment of very good results in terms of selectivity and sensitivity (up to 5.4 × 10−10 mol L−1 and 1.8 × 10−9 mol L−1 for caffeine and theophylline, respectively). Moreover, the ability of GO to protect DNA and RNA from enzymatic digestion renders it one of the best candidates for biosensors based on these nucleic acids. This is an up-to-date review of the use of GO and RGO in sensors.

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Recent progress in nanomaterial-based assay for the detection of phytotoxins in foods

Cited by 30 publications

References 102 publications

Synthesis of Magnetic Metal-Organic Frame Material and Its Application in Food Sample Preparation

Synthesis of Magnetic Metal-Organic Frame Material and Its Application in Food Sample Preparation

Two-Dimensional Layered Nanomaterial-Based Electrochemical Biosensors for Detecting Microbial Toxins

Graphene Oxide: A Smart (Starting) Material for Natural Methylxanthines Adsorption and Detection

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