Recent Progress in Microbiology and Biotechnology Vol. 4

Ikotun, Adebomi A.; Awosika, Oladipupo O.; Oladipo, Mary Adelaide; Al-Haideri, Halah H.; Jwanse, I. R.; Ejinaka, O. R.; Agbalaka, P. I.; Uchejeso, Obeta M.; Ya’aba, Y.; Mohammed, S. B.; Olatunji, K. T.; Usoroh, M.; Daniel, O; Abdul‐Mumin, Alhassan; Yakubu, J. G.; Iosifidis, Εlias; Papachristou, Savvas; Roilides, Emmanuel; Rani, R Prasanna Kumar M Sahitya; Kumar, Sudhir; Eleazar, Clara Idara; Yadav, Sarita; Rammohan, Anu; Cherukuri, S. D.; Kekuda, T.R.Prashith; Mohammadi, Fathima; Nandini, V.; Shreya, K. S.; Abhijith, H. U.; Aleru, Constancy Prisca; Wachukwu, Kinikanwo Confidence; Lakhtin, V. M.; Lakhtin, M. V.; Afanasiev, S. S.; Davydkin, V.Yu.; Алешкин, В. А.; Mohammed, Bawa; Malang, Stipak; Mailafia, S; Agbede, R. I. S.; Iram, Umamah; Naaz, Sumera; Fatima, Nousheen; Margaret, E

doi:10.9734/bpi/rpmb/v4

Cited by 1 publication

(3 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The current modern knowledge on relationships reveals prospects of enzybiotics with lectinic properties and lectinbiotics with enzymatic activities as multifunctional modulators within organism. The latter opens new potential for constructing new generation of enzyme-and lectin-based bioactives and drugs, instruments for biomarker target search and screening possible successful applications in future [41], [43], [45]- [48], [52]- [54], [68], [75].…”

Section: Discussionmentioning

confidence: 99%

“…The data on CBM types variety allow to create new constructs of mono/bi/multi-CBM-containing enzyme molecules/assemblies (enzylectins, postbiotics as enzymes [enzypostbiotics], "enzymes as receptors" [82] or enzycommunicators). They will be useful for probiotic, postbiotic, prebiotic, symbiotic and synbiotic co-functioning systems in organism, organ, tissue, cellular models and bioreactors of industrial, diagnostic and prognostic significance [43], [47], [48], [52], [68], [70]. Another promising possibility may be using probiotic microbial lectins [46]- [48].…”

Section: Prospects Of Lectin-enzyme Relationshipsmentioning

confidence: 99%

“…Another promising possibility may be using probiotic microbial lectins [46]- [48]. It seems, in normal conditions probiotic bifidobacterial and lactobacillar lectin systems are involved in supporting healthy level of the balanced biotope Host-Microbiota [68].…”

Section: Prospects Of Lectin-enzyme Relationshipsmentioning

confidence: 99%

See 2 more Smart Citations

Enzybiotics with Lectin Properties and Lectinbiotics with Enzyme Activities – Multifunctional Modulators of Communications in Organism: Fundamentals and Unlimited Potential in Food Industry, Biosensors and Medicine

Lakhtin

Davydkin

et al. 2021

EJBIO

Self Cite

View full text Add to dashboard Cite

Examples of the nomenclature enzymes of all known classes with intrinsic lectin properties are represented, described and ordered. Such bi/multifunctional enzymes (enzybiotics) act as communicative agents, possess independent carbohydrate binding motifs, domains, epitopes or modules within subunit/molecule or supra-molecular assembly (free or solid-phased). Lectin part serve as modulator, switch and/or navigator of the whole resulting pattern enzyme (involving both catalytic center and lectinic sites) specificities toward targets. These enzybiotics (native and recombinant) as well as lectinbiotics (lectin-biotics) with intrinsic enzyme activities and high communicative potential possess promising broad prospects in food industry, medical biotechnology, prophylaxis and therapy. Among examples there are probiotic lectin enzybiotics (mainly from bifidobacteria and lactobacilli) that can serve perspective metabolite postbiotic systems for support or correction of the healthy individual or the patient mucosal open cavity biotope pathological status, respectively. Lectin-enzyme relationships improve platform for constructing advanced autoregulated systems influencing interactome at all levels of the organism. They support a lot of possible innovations in industrial biotechnology and medicine.

show abstract