Recent Progress in Carbon Nanotube Polymer Composites in Tissue Engineering and Regeneration

Abstract

Scaffolds are important to tissue regeneration and engineering because they can sustain the continuous release of various cell types and provide a location where new bone-forming cells can attach and propagate. Scaffolds produced from diverse processes have been studied and analyzed in recent decades. They are structurally efficient for improving cell affinity and synthetic and mechanical strength. Carbon nanotubes are spongy nanoparticles with high strength and thermal inertness, and they have been used as filler particles in the manufacturing industry to increase the performance of scaffold particles. The regeneration of tissue and organs requires a significant level of spatial and temporal control over physiological processes, as well as experiments in actual environments. This has led to an upsurge in the use of nanoparticle-based tissue scaffolds with numerous cell types for contrast imaging and managing scaffold characteristics. In this review, we emphasize the usage of carbon nanotubes (CNTs) and CNT–polymer composites in tissue engineering and regenerative medicine and also summarize challenges and prospects for their potential applications in different areas.

Growth, Properties, and Applications of Branched Carbon Nanostructures

“…In silico studies of the mechanism of nanowelding a branched network of SWCNTs were performed for tissue engineering applications [4], whereby CNTs are very promising [35,36], especially to repair the bone [37,38] and conductive tissues [39], such as the nerve [40] and the heart [41]. Defective regions of SWCNTs were found to absorb more energy than defect-free regions, which acted as hot-spots for nanowelding and the formation of b-CNT networks [4].…”

“…Finally, researchers in this field can take hope from Herbert Krömer (Nobel Prize in Physics 2000) in Krömer's Lemma: "The principal applications of any sufficiently new and innovative technology always have been and will continue to be applications created by that new technology" [131]. For instance, the unique properties of CNS led to a wide array of proposed applications in medicine and the health sector [132][133][134][135], spanning from tissue engineering [35,136] to wearable sensors [137,138], imaging [139,140], diagnostics, and therapy [141], especially leveraging their conductive properties [142]. There are, however, hurdles for their translation into clinical practice [143][144][145], and it can be envisaged that further developments in their covalent attachment into stable and branched nanostructures may allow at least some of these barriers to be overcome, for instance limiting the loss of individual CNSs from the material.…”

Электростимуляция Дермальных Фибробластов Человека На Электропроводящей Матрице

“…Композиты хитозана и углеродных нанотрубок получены рядом авторов [16][17][18][19]. Изучены их оптические, механические и электропроводящие свойства [20,21].…”

Nitrogen-Doped Multiwalled Carbon Nanotubes Inhibit Fat Deposition via Immunomodulatory Actions

“…Carbon nanotubes (CNTs), as a kind of tube like-structured nanomaterials, have received great interest in the eld of pharmaceutical sciences due to their high penetration power and surface area [2][3][4][5]. CNTs can be divided into two categories: single-walled carbon nanotubes (SWCNTs) and multi-walled carbon nanotubes (MWCNTs) [5].…”

“…Carbon nanotubes (CNTs), as a kind of tube like-structured nanomaterials, have received great interest in the eld of pharmaceutical sciences due to their high penetration power and surface area [2][3][4][5]. CNTs can be divided into two categories: single-walled carbon nanotubes (SWCNTs) and multi-walled carbon nanotubes (MWCNTs) [5]. Compared with SWCNTs, MWCNTs are composed of multi-layer graphene and have a much wider diameter adjustment range, so they provide a variety of research methods for different biological purposes, such as delivering some large biomolecules and drugs to the cells [6][7][8][9].…”