Recent insights into polysaccharide-based hydrogels and their potential applications in food sector: A review

Manzoor, Arshied; Dar, Aamir Hussain; Pandey, Vinay Kumar; Shams, Rafeeya; Khan, Sadeeya; Panesar, Parmjit S.; Kennedy, John F.; Fayaz, Ufaq; Khan, Shafat Ahmad

doi:10.1016/j.ijbiomac.2022.06.044

Cited by 140 publications

(64 citation statements)

References 246 publications

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“…Organic gels such as PEGs are much more exploited lately as they play a significant role in formulating food flavour carrier systems. At the same time, they have multiple benefits for food applications considering that they prolong the stability and the shelf-life of the products incorporating them [ 19 , 70 ].…”

Section: Applicability Of Polysaccharide-based Edible Gelsmentioning

confidence: 99%

“…The organic gels used for food designing, preparation, and enhancement of structural stability are edible biopolymers which are declared as Generally Recognized As Safe (GRAS) by the Food and Drug Administration (FDA) [ 19 , 71 ]. Biopolymers such as sodium alginate, chitosan, agarose, starch, pectin, agar-agar, or hyaluronic acid create 3D structures that facilitate the integration of some bioactive molecules, water, or oils in the mesh of the network, giving the FERM structure of gels that can be shaped into a variety of sizes and forms, the system that is highly desired in both traditional and modern gastronomy preparations [ 72 , 73 , 74 , 75 ].…”

Section: Applicability Of Polysaccharide-based Edible Gelsmentioning

confidence: 99%

“…One of the main factors that can help enhance obesity is their role as a carrier for bioactive compounds. Delivery setups have been developed to prevent the deterioration of sensitive chemical components during the food production processes, as well as enzymes for digestion and harsh environmental conditions and area-specific gastro-intestinal transportation and controlled release of hydrophilic and hydrophobic nutraceuticals [ 19 ]. Lipid-dependent networks, biopolymers, and systems inspired by nature, such as PEGs, are the most used types of delivery methods.…”

Section: Health Benefits Of Pegsmentioning

confidence: 99%

“…Furthermore, PEGs facilitate the adsorption of such compounds into the intestines [ 17 , 18 ]. With respect to above-mentioned applications hydrogels was critically discussed and considering their immense potential, further studies have an ample scope [ 19 ]. Furthermore, oleogels represent promising alternatives to solid fats for food application and their recent advances in food application was critically discuses [ 20 ].…”

Section: Introductionmentioning

confidence: 99%

“…Obesity can be managed by using PEGs due to their properties to deliver both hydrophobic and hydrophilic nutraceuticals in a controlled manner. PEGs, such as hydrogels, can protect bioactive compounds through the gastro-intestinal tract [ 18 , 19 , 28 ]. The past five years have seen tremendous report research on PEG development and its valuable applicability.…”

Section: Introductionmentioning

confidence: 99%

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Polysaccharide-Based Edible Gels as Functional Ingredients: Characterization, Applicability, and Human Health Benefits

Pascuta

Varvara

Teleky

et al. 2022

Gels

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Nowadays, edible materials such as polysaccharides have gained attention due to their valuable attributes, especially gelling property. Polysaccharide-based edible gels (PEGs) can be classified as (i) hydrogels, (ii) oleogels and bigels, (iii) and aerogels, cryogels and xerogels, respectively. PEGs have different characteristics and benefits depending on the functional groups of polysaccharide chains (e.g., carboxylic, sulphonic, amino, methoxyl) and on the preparation method. However, PEGs are found in the incipient phase of research and most studies are related to their preparation, characterization, sustainable raw materials, and applicability. Furthermore, all these aspects are treated separately for each class of PEG, without offering an overview of those already obtained PEGs. The novelty of this manuscript is to offer an overview of the classification, definition, formulation, and characterization of PEGs. Furthermore, the applicability of PEGs in the food sector (e.g., food packaging, improving food profile agent, delivery systems) and in the medical/pharmaceutical sector is also critically discussed. Ultimately, the correlation between PEG consumption and polysaccharides properties for human health (e.g., intestinal microecology, “bridge effect” in obesity, gut microbiota) are critically discussed for the first time. Bigels may be valuable for use as ink for 3D food printing in personalized diets for human health treatment. PEGs have a significant role in developing smart materials as both ingredients and coatings and methods, and techniques for exploring PEGs are essential. PEGs as carriers of bioactive compounds have a demonstrated effect on obesity. All the physical, chemical, and biological interactions among PEGs and other organic and inorganic structures should be investigated.

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Section: Applicability Of Polysaccharide-based Edible Gelsmentioning

confidence: 99%

Section: Applicability Of Polysaccharide-based Edible Gelsmentioning

confidence: 99%

Section: Health Benefits Of Pegsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Polysaccharide-Based Edible Gels as Functional Ingredients: Characterization, Applicability, and Human Health Benefits

Pascuta

Varvara

Teleky

et al. 2022

Gels

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Advancing biomedicine with gel‐based materials and composites: A comprehensive review

Sajjadi,

Gholizadeh‐Hashjin,

Shafizadeh

et al. 2023

J of Applied Polymer Sci

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Polymer gels are an important class of soft materials with growing interest for biomedical applications due to their distinctive properties. These three‐dimensional polymer networks are capable of imbibing large amounts of solvent while maintaining solid‐like behavior. Polymer gels can be classified into hydrogels, aerogels, and cryogels based on their structural features. Their highly porous structure, swelling capacity, and biocompatibility make them well‐suited for diverse uses in biomedicine. Recent advances have enabled the engineering of polymer gels with tunable architectures and smart functionality responsive to stimuli. These developments have expanded the potential of gels in areas like tissue engineering, drug delivery, wound healing, and biosensing. However, the toxicity of polymer gels remains an important consideration for biomedical use. Careful design and toxicological evaluation is essential to ensure safe clinical application. Overall, polymer gels offer new possibilities in biomedicine through continued research on synthesizing biocompatible gels and elucidating structure–function relationships. This review provides an updated perspective on the progress and promise of tailoring polymer gels to advance biomedicine, while also considering the critical aspect of biocompatibility.

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Mussel‐mimetic polysaccharide‐based injectable hydrogels for biomedical applications

Fan,

Zheng,

Jin

et al. 2024

BMEMat

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With high biocompatibility and degradability, polysaccharide‐based hydrogels are favorable healthcare materials. However, in many biomedical applications, these materials are inconvenient to handle with fixed morphology, unable to closely match the wounds, and easy to detach due to insufficient adhesion. Inspired by the superior wet adhesive properties of marine mussels, researchers have used mussel‐inspired chemistry to create mussel‐mimetic injectable polysaccharide‐based hydrogels that are simple to operate, controllable in shape, and highly adhesive, and have significantly extended their applications such as tissue adhesives, delivery vehicles, tissue engineering scaffolds, and wearable sensors. However, there are few comprehensive reviews on polysaccharide‐based hydrogels with both mussel‐mimetic adhesion and injectability, and few critical analyses of these hydrogels' preparation methods and applications. This review fills this gap and systematically summarizes the preparation strategies for novel mussel‐mimetic injectable polysaccharide‐based hydrogels, including modifying polysaccharides with catechol‐ or pyrogallol‐containing small molecules and leveraging different interactions between catechol‐/pyrogallol‐modified polysaccharides and other substances to form crosslinked hydrogels. Furthermore, recent biomedical applications of injectable catechol‐/pyrogallol‐modified polysaccharide‐based hydrogels are discussed, and their future challenges and research trends are proposed.

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Recent insights into polysaccharide-based hydrogels and their potential applications in food sector: A review

Cited by 140 publications

References 246 publications

Polysaccharide-Based Edible Gels as Functional Ingredients: Characterization, Applicability, and Human Health Benefits

Polysaccharide-Based Edible Gels as Functional Ingredients: Characterization, Applicability, and Human Health Benefits

Advancing biomedicine with gel‐based materials and composites: A comprehensive review

Mussel‐mimetic polysaccharide‐based injectable hydrogels for biomedical applications

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