Recent developments in the synthesis of biologically active indole alkaloids

Labo, A. M.; Prabhakar, Sundaresan

doi:10.1002/jhet.5570390301

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Cited by 25 publications

(1 citation statement)

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“…Inhibition of protein kinases A and C and of protein tyrosine kinase (PTK) has been described (Steglich, 1989;Toullec et al, 1991;Lakatosh et al, 2002). These bisindolylimides and their derivatives are, in contrast to indolo[2,3-a] carbazoles, not bridged at their indole-2-positions and show different biological activies (Routier et al, 2002;Caballero et al, 2003;Lobo and Prabhakar, 2002;Slater et al, 2001). Therefore, they are also named secoindolocarbazoles (Link et al, 1995).…”

Section: Alkaloidsmentioning

confidence: 95%

Secondary metabolites of slime molds (myxomycetes)

et al. 2005

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Section: Alkaloidsmentioning

confidence: 95%

Secondary metabolites of slime molds (myxomycetes)

et al. 2005

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Palladium‐Catalyzed One‐Pot Consecutive Amination and Sonogashira Coupling for Selective Synthesis of 2‐Alkynylanilines

Pan

Zhong

et al. 2015

Adv Synth Catal

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An efficientcatalytic approach to the synthesis of N,N-dialkyl-2-alkynylanilinesw as developed by using Pd-catalyzed norbornene-mediated three-component reactions of haloarenes, alkoxyamines (RO-NR 2 ), and alkynes. Thep rocedure forms one C À Nb onda nd one C À Cb onde fficiently in ao ne-pot manner from readily available starting materials.Anumber of 2-alkynylanilinesw ith ab road range of functional groups were afforded in good to excellent yields.

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