Recent Developments in High-Performance Liquid Chromatography Stationary Phases

Chester, T. L.

doi:10.1021/ac303180y

Cited by 125 publications

(75 citation statements)

References 238 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Limitations related to particle size were also discussed in a recent review. 10 The upper limit of packable column length is also decreased with the decrease of particle size. Thus the net effect of decreasing particle size is to reduce the analysis time with the same separation efficiency under an increased operation pressure.…”

Section: Critical Overview On Feasibilities Of Various Types Of Silicmentioning

confidence: 98%

“…Superficially porous (core/ shell) sub-3 µm silica particles have also been prepared recently. 2,3,7,10,[19][20][21][22][23][24][25][26][27][28][29][30] Nonporous Silica Particles. Nonporous silica particles have been used for quick separation of peptides and proteins.…”

Section: Sub 3 µM Silica Particlesmentioning

confidence: 99%

“…9 In addition, a review on numerous recent developments of HPLC stationary phases was given in 2013 including small particles (including coreshell), monoliths, hydrophilic interaction chromatography (HILIC) phases, and mixed mode phases. 10 Use of silicahydride stationary phases in aqueous normal phase liquid chromatography was reviewed in 2013.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Porous Silica Particles As Chromatographic Separation Media: A Review

Cheong¹

2014

Bulletin of the Korean Chemical Society

View full text Add to dashboard Cite

Porous silica particles are the most prevailing raw material for stationary phases of liquid chromatography. During a long period of time, various methodologies for production of porous silica particles have been proposed, such as crashing and sieving of xerogel, traditional dry or wet process preparation of conventional spherical particles, preparation of hierarchical mesoporous particles by template-mediated pore formation, repeated formation of a thin layer of porous silica upon nonporous silica core (core-shell particles), and formation of specific silica monolith followed by grinding and calcination. Recent developments and applications of useful porous silica particles will be covered in this review. Discussion on sub-3 µm silica particles including nonporous silica particles, carbon or metal oxide clad silica particles, and molecularly imprinted silica particles, will also be included. Next, the individual preparation methods and their feasibilities will be collectively and critically compared and evaluated, being followed by conclusive remarks and future perspectives.

show abstract

Section: Critical Overview On Feasibilities Of Various Types Of Silicmentioning

confidence: 98%

Section: Sub 3 µM Silica Particlesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Porous Silica Particles As Chromatographic Separation Media: A Review

Cheong¹

2014

Bulletin of the Korean Chemical Society

View full text Add to dashboard Cite

show abstract

“…However, some limitations are associated with the use of these phases, such as frictional heating, which occurs at ultra-high pressures [107]. Therefore, attempts have been made to find alternative stationary phase morphologies to overcome some of the shortcomings of porous silica.…”

Section: Alternative Stationary Phase Morphologiesmentioning

confidence: 99%

“…This means that these columns can also be used on conventional HPLC instruments. In addition, the recent availability of high-pressure resistant superficially porous phases extends their use to UHPLC instruments, where improved performance compared to UHPLC columns of the same particle size can be obtained [107].…”

Section: Alternative Stationary Phase Morphologiesmentioning

confidence: 99%