Recent Advances in the Reaction of MBH Carbonates: Scope and Mechanism

Abstract

In recent years, Morita‐Baylis‐Hillman (MBH) carbonates have been extensively used in domino reactions for the synthesis of novel heterocyclic or chain compounds. This review aims to highlight the progress made in the last decade in the synthesis of a series of compounds from the uncyclized reaction or annulation of MBH carbonates. Most of the work mentioned in this review strongly demonstrates that MBH carbonates have excellent reaction activity and research value as a representative substrate in the field of organic synthesis. We hope the summary and understanding of the reactivity of MBH carbonates can inspire chemists to apply these substrates in the design of more efficient domino reactions, which may be beneficial for the organic synthesis and drug chemistry.