Recent Advances in Rhodium‐Catalyzed Electrochemical C−H Activation

Abstract

Rhodium-catalyzed CÀ H activation has emerged as a powerful tool for forging CÀ C and C-heteroatom bonds. Nevertheless, the requirement of stoichiometric chemical oxidants for oxidative transformations significantly hampered the overall sustainability of the CÀ H activation transformations. The emergence of merging transition metal catalysis and electrochemistry, called metalla-electrocatalysis provides an excellent opportunity to construct organic molecules efficiently and sustainably. This review highlights the recent developments of rhodium-catalyzed electrochemical CÀ H activation transformations, challenges and opportunities for future developments.

Ruthenium(II)-Catalyzed [4 + 2] Electro-Oxidative Annulation of C6-Arylpurines/Purine Nucleosides

“…They possess the ability to circumvent the use of costly and often toxic chemical oxidants and also offer to provide a mechanistically distinct catalytic model compared to thermal conditions . While rhodium electrocatalysis is extensively researched, exploration of economically advantageous ruthenium electrocatalysis still remains underdeveloped …”