Recent Advances in Pancreatic Transplantation

Iacovidou, Aphrodite; Hakim, Nadey

doi:10.6002/ect.2013.0231

Cited by 2 publications

(1 citation statement)

References 8 publications

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“…In the recipient, preparation of the pancreas involves a "Y" or trouser graft vascular anastomosis of the superior mesenteric artery and splenic artery using the donor iliac bifurcation graft and tying off small branches and lymphatics to gain hemostasis. 34,35 The recipient undergoes a laparotomy. The iliac vessels are divided and prepared, while the graft portal vein anastomosis to the recipient's right common iliac vein or inferior vena cava gives systemic release of the endocrine pancreas (insulin, glucagon); the graft portal artery is anastomosed to the right common iliac artery, and the exocrine graft secretions are drained enterically using a side-to-side ileumeduodenum anastomosis 35 (Figure).…”

Section: Current Surgical Proceduresmentioning

confidence: 99%

Pancreas Transplantation: Past, Present, Future

Dholakia

Mittal

Quiroga

et al. 2016

The American Journal of Medicine

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Diabetes is the pandemic disease of the modern era, with 10% of these patients having type 1 diabetes mellitus. Despite the prevalence, morbidities, and associated financial burden, treatment options have not changed since the introduction of injectable insulin. To date, over 40,000 pancreas transplants have been performed globally. It remains the only known method for restoring glycemic control and thus curing type 1 diabetes mellitus. The aim of this review is to bring pancreatic transplantation out of the specialist realm, informing practitioners about this important procedure, so that they feel better equipped to refer suitable patients for transplantation and manage, counsel, and support when encountering them within their own specialty. This study was a narrative review conducted in October 2015, with OVID interface searching EMBASE and MEDLINE databases, using Timeframe: Inception to October 2015. Articles were assessed for clinical relevance and most up-to-date content, with articles written in English as the only inclusion criterion. Other sources used included conference proceedings/presentations and unpublished data from our institution (Oxford Transplant Centre). Pancreatic transplantation is growing and has quickly become the gold standard of care for patients with type 1 diabetes mellitus and renal failure. Significant improvements in quality of life and life expectancy make pancreatic transplant a viable and economically feasible intervention. It remains the most effective method of establishing and maintaining euglycemia, halting and potentially reversing complications associated with diabetes.

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Section: Current Surgical Proceduresmentioning

confidence: 99%

Pancreas Transplantation: Past, Present, Future

Dholakia

Mittal

Quiroga

et al. 2016

The American Journal of Medicine

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Global scientific trends on the islet transplantation in the 21st century: A bibliometric and visualized analysis

Chen,

Wu,

Zhang

et al. 2024

Medicine

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Background: Islet transplantation (IT) has emerged as a significant research area for the treatment of diabetes mellitus and has witnessed a surge in scholarly attention. Despite its growing importance, there is a lack of bibliometric analyses that encapsulate the evolution and scientific underpinnings of this field. This study aims to fill this gap by conducting a comprehensive bibliometric analysis to delineate current research hotspots and forecast future trajectories within the IT domain with a particular focus on evidence-based medicine practices. Methods: This analysis scrutinized literature from January 1, 2000, to October 1, 2023, using the Web of Science Core Collection (WoSCC). Employing bibliometric tools such as VOSviewer, CiteSpace, and the R package “bibliometrix,” we systematically evaluated the literature to uncover scientific trends and collaboration networks in IT research. Results: The analysis revealed 8388 publications from 82 countries, predominantly the United States and China. However, global cross-institutional collaboration in IT research requires further strengthening. The number of IT-related publications has increased annually. Leading research institutions in this field include Harvard University, the University of Alberta, the University of Miami, and the University of Minnesota. “Transplantation” emerges as the most frequently cited journal in this area. Shapiro and Ricordi were the most prolific authors, with 126 and 121 publications, respectively. Shapiro also led to co-citations, totaling 4808. Key research focuses on IT sites and procedures as well as novel therapies in IT. Emerging research hotspots are identified by terms like “xenotransplantation,” “apoptosis,” “stem cells,” “immunosuppression,” and “microencapsulation.” Conclusions: The findings underscore a mounting anticipation for future IT research, which is expected to delve deeper into evidence-based methodologies for IT sites, procedures, and novel therapeutic interventions. This shift toward evidence-based medicine underscores the field’s commitment to enhancing the efficacy and safety of IT for diabetes treatment, signaling a promising direction for future investigations aimed at optimizing patient outcomes.

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Recent Advances in Pancreatic Transplantation

Cited by 2 publications

References 8 publications

Pancreas Transplantation: Past, Present, Future

Pancreas Transplantation: Past, Present, Future

Global scientific trends on the islet transplantation in the 21st century: A bibliometric and visualized analysis

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