Recent Advances in Nanoparticles-based Lateral Flow Biosensors

Abstract

Lateral flow biosensors (LFBs) provide advantages in low cost, simplicity, rapidity, stability and portability, thus making LFBs popular in biomedical, agriculture, food and environmental sciences. This article reviews recent advances of LFBs for bioassays, including the investigation of the improvements achieved by signal-amplification strategies, the application of new nanoparticle labels, novel quantitative system and simultaneous detection. We summarized the outstanding performances of LFBs such as high detection sensitivity, specificity, reproducibility and reliability.

A mini-review on functional nucleic acids-based heavy metal ion detection

“…Originally the LFAs was used in human chorionic gonadotrophin (HCG) immunoassay and called "sol particle immunoassay" (SPIA) (Leuvering et al, 1980), and now it have been widely applied in environmental monitoring, food safety, and clinical diagnosis for visual (qualitative) and quantitative detecting of various biomolecules (Liu et al, 2006) and chemical contaminants (Chen and Yang 2015;Gao et al, 2014). Generally, the LFA devices consisted of four overlapping pads sticking to a backing.…”

Fe3O4@MOF Magnetic Nanocomposites: Synthesis and Applications

“…Another material that has been the center of attention among researches who work on new materials with new applications is magnetic nanoparticles (MNPs) . Magnetic fluids, catalysis, biotechnology/biomedicine, magnetic resonance imaging, data storage, and environmental remediation are some of the applications in which MNPs can play a crucial role.…”

Self‐doped N‐propansulfonic acid polyaniline‐polyethylene terephthalate film used as active sensor element for humidity or gas detection

“…Therefore, much effort has been made to improve the major drawbacks, like lack of processability and solubility of the conducting PANi and many attempts have been made to surpass these difficulties . Sulfonated PANis are the alternative way used to solve the problems of polymer solubility and processability, because the presence of these groups in PANi structure affects the physicochemical properties of parent‐polymer and is of great interest in crystallographic, optical, steric, and electronic properties . Sulfonated PANis are obtained by several routes such as copolymerization of aniline with aniline comonomers containing sulfonic groups, the direct ring‐sulfonation of emeraldine base form with fuming sulfuric acid, when –SO 3 H groups are introduced at the aromatic ring, the treatment of emeraldine base of PANi with 1,3‐propanesulfone or 1,4‐butanesulfone in the presence of sodium hydride, and chemical and electrochemical polymerization of sulfonated monomers .…”