Recent advances in nanomaterial-based biosensors for antibiotics detection

Lan, Lingyi; Yao, Yao; Ping, Jianfeng; Ying, Yibin

doi:10.1016/j.bios.2017.01.007

Cited by 348 publications

(137 citation statements)

References 89 publications

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“…Especially, aptamers that recognize antibiotic-resistance markers and antibiotics are in high demand because of the emerging antimicrobial resistance that increases morbidity, mortality and healthcare costs (Solomon and Oliver, 2014;Fridkin et al, 2015;Frieri et al, 2017;H.M. Kwon et al, 2014b;Chen et al, 2017;Yan et al, 2016;Lan et al, 2017). Kwon et al, 2014b;Chen et al, 2017;Yan et al, 2016;Lan et al, 2017).…”

Section: Future Perspectivesmentioning

confidence: 99%

Nucleic acid aptamer-based methods for diagnosis of infections

Park

2018

Biosensors and Bioelectronics

136

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Infectious diseases are a serious global problem, which not only take an enormous human toll but also incur tremendous economic losses. In combating infectious diseases, rapid and accurate diagnostic tests are required for pathogen identification at the point of care (POC). In this review, investigations of diagnostic strategies for infectious diseases that are based on aptamers, especially nucleic acid aptamers, oligonucleotides that have high affinities and specificities toward their targets, are described. Owing to their unique features including low cost of production, easy chemical modification, high chemical stability, reproducibility, and low levels of immunogenicity and toxicity, aptamers have been widely utilized as bio-recognition elements (bio-receptors) for the development of infection diagnostic systems. We discuss nucleic acid aptamer-based methods that have been developed for diagnosis of infections using a format that organizes discussion according to the target pathogenic analytes including toxins or proteins, whole cells and nucleic acids. Also included is, a summary of recent advances made in the sensitive detection of pathogenic bacteria utilizing the isothermal nucleic acid amplification method. Lastly, a nucleic acid aptamer-based POC system is described and future directions of studies in this area are discussed.

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Section: Future Perspectivesmentioning

confidence: 99%

Nucleic acid aptamer-based methods for diagnosis of infections

Park

2018

Biosensors and Bioelectronics

136

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“…These techniques offer much scope for rapid and sensitive detection of microbes in disease pathology or food industries. By taking advantage of the technical supremacy, several biolabel technologies were developed using nanomaterials for detecting antibiotics and food contaminants (Turner, ; Lan et al., , ). Chemiluminescence and bioluminescence emission act as a signal in several of these applications, wherein these molecules were used as tags for detection (Wang, Xu et al., ).…”

Section: Biolabelsmentioning

confidence: 99%

Current technological trends in biosensors, nanoparticle devices and biolabels: Hi‐tech network sensing applications

Vigneshvar

Senthilkumaran

2018

Med Devices & Sens

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Biosensors are micro‐analytical devices usually coupled to a bio‐integrated transducer that emits signal to measure specific molecules as an analyte, either qualitatively or quantitatively for various downstream applications. Improved detection methods at quantum level in nanoscale became a reality due to the invention of integrated circuits involving nanoparticle devices and biolabels. Next level of discoveries leads to the identification of novel particulates to improve the specificity and sensitivity for single analyte detection. Although different kinds of biosensors show promise for multifaceted applications in science and technology, certain limitations do exist in terms of portability, selectivity and sensitivity as well as in multi‐analyte detection. Recent methodical advancements involving nanomaterials or nanoparticles/metals in combination with biomarkers or biolabels as sensors provide new insights to solve these limitations to prepare flawless detecting devices. These technical advances are evident in modern‐day sensors including hand‐held, smartphone‐based, wearable and flexible sensors developed for multifaceted applications. This concise review article describes the new technological trends in the development of biosensors integrated to nanoparticle devices and/or biolabels involving hi‐tech network system for better efficiency. Future perspectives on new technological developments for effective combination of several nanomaterials and biolabels with strategic engineering methodology were highlighted.

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“…Antibiotics have been widely used to treat animal diseases and promote animal growth , . Penicillin, as one kind of β‐lactam antibiotics, has been most widely applied because of its broad spectrum antibiotic activity .…”

Section: Introductionmentioning

confidence: 99%

Halide‐directed Assembly of Mercury(II) Coordination Polymers for Electrochemical Biosensing Toward Penicillin

Xue

Chen

2020

Zeitschrift anorg allge chemie

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Three 1D/2D HgII coordination polymers (CPs), namely {[Hg3(L)2Cl6](H2O)}n (1), [Hg(L)Br2]n (2), and [Hg(L)I2]n (3) were prepared by assembly of 3,4‐bis(3‐pyridyl)‐5‐(4‐pyridyl)‐1,2,4‐triazole (L) with different inorganic HgII salts (i.e. HgCl2, HgBr2 or HgI2). Single‐crystal X‐ray diffraction analysis reveals two types of bimetallic subunits [(Hg)2C6N4] and [(Hg)2C12N6] in CP 1, which are further extended to a 2D coordination network. Both of CPs 2 and 3 show 1D zigzag arrays bridged by L ligands. Notably, the L ligands take the (η4, μ4) coordination fashion in 1 but (η2, μ2) binding mode in 2 and 3. The structural differences of CPs 1–3 indicate that the L ligand can adjust its coordination fashions to meet the requirements of HgII centers, relying on the presence of distinct halide anions. In addition, 1 can be applied to fabricate an electrochemical biosensor for the detection of penicillin.

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Recent advances in nanomaterial-based biosensors for antibiotics detection

Cited by 348 publications

References 89 publications

Nucleic acid aptamer-based methods for diagnosis of infections

Nucleic acid aptamer-based methods for diagnosis of infections

Current technological trends in biosensors, nanoparticle devices and biolabels: Hi‐tech network sensing applications

Halide‐directed Assembly of Mercury(II) Coordination Polymers for Electrochemical Biosensing Toward Penicillin

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