Recent Advances in Intravenous Anaesthesia

Sear, J.W.

doi:10.1111/j.1467-2995.1991.tb00505.x

Cited by 1 publication

(1 citation statement)

References 36 publications

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“…Besides metabolism by the liver, extrahepatic sites of metabolism, most prominently the lung, have been claimed for propofol 15 . Propofol causes a dose-related decrease in blood pressure due to peripheral vasodilation and myocardial depression, bradycardia, epileptiform seizures and true convulsions 4,30 . When administered at a dose of 4-7 mg/kg intravenously in unpremedicated goats and sheep, propofol will induce sufficient anaesthesia for endotracheal intubation 25,27 , while 3 mg/kg was shown to be sufficient for endotracheal intubation in premedicated goats 3 .…”

Section: Introductionmentioning

confidence: 99%

Sedative and cardiopulmonary effects of acepromazine, midazolam, butorphanol, acepromazine-butorphanol and midazolam-butorphanol on propofol anaesthesia in goats

Dzikiti¹,

Stegmann²,

Hellebrekers³

et al. 2009

J. S. Afr. Vet. Assoc.

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The study was conducted to study the effect of acepromazine and midazolam along with ketamin on haematological parameters in yak. Twelve clinically healthy yaks of either sex and below 2 years of age from yak farm of ICAR-National Research Centre on Yak, Dirang, Arunachal Pradesh were selected for the study. Yak were randomly divided into two groups, Group AK and Group MK i.e. six animals in each group. The animals in Group AK received acepromazine @0.1mg/kg body weight IM followed by ketamine @2.5mg/kg body weight IM after 15 minutes and the animals in Group MK received midazolam @0.5mg/kg body weight IM followed by ketamine @2.5mg/kg body weight IM after 15 minutes. Venous blood samples were collected at 0 (baseline) and at 15, 30, 60 and 90 minutes after administration of anaesthetic agents to monitor the haematological parameters which included haemoglobin, packed cell volume, total erythrocyte count and total leukocyte count. The changes in haematological parameters in both the group were within the normal physiological limit. Based on the findings, both the anaesthetic combinations were found safe to be used in yak.

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