Recent Advances in Inflammatory Diagnosis with Graphene Quantum Dots Enhanced SERS Detection

Mousavi, Seyyed Mojtaba; Hashemi, Seyyed Alireza; Kalashgrani, Masoomeh Yari; Kurniawan, Darwin; Gholami, Ahmad; Rahmanian, Vahid; Omidifar, Navid; Chiang, Wei‐Hung

doi:10.3390/bios12070461

Cited by 29 publications

(17 citation statements)

References 150 publications

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“…Photostability, light bleaching resistance, and nonscintillation are CQDs’ features, and QD carbon has excellent fluorescence properties compared to traditional fluorescent dyes. CQDs are safer and non-toxic at cellular and animal levels [ 90 , 91 , 95 ] and are desirable options for nanomedical applications due to the absence of visible signs of toxicity in animals, excellent water dispersion, and an average diameter of less than 10 nm [ 96 , 97 ]. Due to good biocompatibility, CQDs can be used as fluorescent probes for biosensing [ 98 , 99 ].…”

Section: Qd-based Nanobiosensorsmentioning

confidence: 99%

The Pivotal Role of Quantum Dots-Based Biomarkers Integrated with Ultra-Sensitive Probes for Multiplex Detection of Human Viral Infections

et al. 2022

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The spread of viral diseases has caused global concern in recent years. Detecting viral infections has become challenging in medical research due to their high infectivity and mutation. A rapid and accurate detection method in biomedical and healthcare segments is essential for the effective treatment of pathogenic viruses and early detection of these viruses. Biosensors are used worldwide to detect viral infections associated with the molecular detection of biomarkers. Thus, detecting viruses based on quantum dots biomarkers is inexpensive and has great potential. To detect the ultrasensitive biomarkers of viral infections, QDs appear to be a promising option as biological probes, while physiological components have been used directly to detect multiple biomarkers simultaneously. The simultaneous measurement of numerous clinical parameters of the same sample volume is possible through multiplex detection of human viral infections, which reduces the time and cost required to record any data point. The purpose of this paper is to review recent studies on the effectiveness of the quantum dot as a detection tool for human pandemic viruses. In this review study, different types of quantum dots and their valuable properties in the structure of biomarkers were investigated. Finally, a vision for recent advances in quantum dot-based biomarkers was presented, whereby they can be integrated into super-sensitive probes for the multiplex detection of human viral infections.

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Section: Qd-based Nanobiosensorsmentioning

confidence: 99%

The Pivotal Role of Quantum Dots-Based Biomarkers Integrated with Ultra-Sensitive Probes for Multiplex Detection of Human Viral Infections

et al. 2022

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“…The functionalized GQDs have enormous applications, such as drug delivery, bioimaging, batteries, sensors, etc. [ 59 , 60 , 61 ]. Recently, the synthesis of QDs from various bioresources has been influenced by the development of green and sustainable chemistry [ 62 , 63 , 64 ].…”

Section: Modification Of Qds With Bioresourcementioning

confidence: 99%

Bioresource-Functionalized Quantum Dots for Energy Generation and Storage: Recent Advances and Feature Perspective

et al. 2022

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The exponential increase in global energy demand in daily life prompts us to search for a bioresource for energy production and storage. Therefore, in developing countries with large populations, there is a need for alternative energy resources to compensate for the energy deficit in an environmentally friendly way and to be independent in their energy demands. The objective of this review article is to compile and evaluate the progress in the development of quantum dots (QDs) for energy generation and storage. Therefore, this article discusses the energy scenario by presenting the basic concepts and advances of various solar cells, providing an overview of energy storage systems (supercapacitors and batteries), and highlighting the research progress to date and future opportunities. This exploratory study will examine the systematic and sequential advances in all three generations of solar cells, namely perovskite solar cells, dye-sensitized solar cells, Si cells, and thin-film solar cells. The discussion will focus on the development of novel QDs that are economical, efficient, and stable. In addition, the current status of high-performance devices for each technology will be discussed in detail. Finally, the prospects, opportunities for improvement, and future trends in the development of cost-effective and efficient QDs for solar cells and storage from biological resources will be highlighted.

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“…If plasmonic nanostructures are coupled with other optical probes, e.g., fluorescent molecules or Raman molecules, they may greatly enhance the optical signal and improve the signal-to-noise ratio of these probes through different chemical processes and physical mechanisms [ 121 , 122 , 123 ]. For example, surface-enhanced Raman spectroscopy (SERS) uses plasmonic nanostructures to enhance the Raman scattering of nearby molecules, which has been broadly used in the detection and biosensing of biological molecules and various viruses [ 124 , 125 , 126 , 127 , 128 , 129 ].…”

Section: Responsive Nanostructured Materials For Viral Disease Biosen...mentioning

confidence: 99%

Smart Nanostructured Materials for SARS-CoV-2 and Variants Prevention, Biosensing and Vaccination

Wang

2022

Biosensors

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The coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has raised great concerns about human health globally. At the current stage, prevention and vaccination are still the most efficient ways to slow down the pandemic and to treat SARS-CoV-2 in various aspects. In this review, we summarize current progress and research activities in developing smart nanostructured materials for COVID-19 prevention, sensing, and vaccination. A few established concepts to prevent the spreading of SARS-CoV-2 and the variants of concerns (VOCs) are firstly reviewed, which emphasizes the importance of smart nanostructures in cutting the virus spreading chains. In the second part, we focus our discussion on the development of stimuli-responsive nanostructures for high-performance biosensing and detection of SARS-CoV-2 and VOCs. The use of nanostructures in developing effective and reliable vaccines for SARS-CoV-2 and VOCs will be introduced in the following section. In the conclusion, we summarize the current research focus on smart nanostructured materials for SARS-CoV-2 treatment. Some existing challenges are also provided, which need continuous efforts in creating smart nanostructured materials for coronavirus biosensing, treatment, and vaccination.

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Recent Advances in Inflammatory Diagnosis with Graphene Quantum Dots Enhanced SERS Detection

Cited by 29 publications

References 150 publications

The Pivotal Role of Quantum Dots-Based Biomarkers Integrated with Ultra-Sensitive Probes for Multiplex Detection of Human Viral Infections

The Pivotal Role of Quantum Dots-Based Biomarkers Integrated with Ultra-Sensitive Probes for Multiplex Detection of Human Viral Infections

Bioresource-Functionalized Quantum Dots for Energy Generation and Storage: Recent Advances and Feature Perspective

Smart Nanostructured Materials for SARS-CoV-2 and Variants Prevention, Biosensing and Vaccination

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