Recent advances in horizontal alveolar bone regeneration

Abstract

Alveolar bone loss is widespread in all age groups and remains a severe hazard to periodontal health. Horizontal alveolar bone loss is the pattern of bone loss more commonly seen in periodontitis. Until now, limited regenerative procedures have been applied to treating horizontal alveolar bone loss in periodontal clinics, making it the least predictable periodontal defect type. This article reviews the literature on recent advances in horizontal alveolar bone regeneration. The biomaterials and clinical and preclinical approaches tested for the regeneration of the horizontal type of alveolar bone are first discussed. Furthermore, current obstacles for horizontal alveolar bone regeneration and future directions in regenerative therapy are presented to provide new ideas for developing an effective multidisciplinary strategy to address the challenge of horizontal alveolar bone loss.

Emerging roles of hydrogel in promoting periodontal tissue regeneration and repairing bone defect

“…Part of periodontitis patients have bone defects, promoting bone regeneration in the area to restore normal chewing function is particularly important for patients with periodontitis combined with bone defects ( Li et al, 2023 ). The repair and regeneration of bone defects is a challenging and highly demanding research.…”

Recent Advances in Scaffolds for Guided Bone Regeneration

“…Guided bone regeneration is a frequently applied and predictable technique to restore bone defects in the maxillofacial region. Depending on the defect’s morphology and severity of bone loss, concepts such as vertical and horizontal bone regeneration have been widely explored [ 40 , 41 , 42 ]. These two aspects strongly influence the type, extent, and prognosis of the rehabilitation procedure [ 43 ].…”