Recent advances in food colloidal delivery systems for essential oils and their main components

Doost, Ali Sedaghat; Nasrabadi, Maryam Nikbakht; Kassozi, Vincent; Nakisozi, Henriettah; Meeren, Paul Van der

doi:10.1016/j.tifs.2020.03.037

Cited by 111 publications

(46 citation statements)

References 98 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In addition, their low water solubility and bioavailability hamper the clinical use of EOs. Therefore, encapsulation has been widely used to overcome such limitations but also to ensure targeted delivery and to boost the antimicrobial efficacy of EOs [92,107,110,111].…”

Section: Encapsulation Of Essential Oils: Chitosomes Vs Liposomes Nmentioning

confidence: 99%

Chitosan-Coating Effect on the Characteristics of Liposomes: A Focus on Bioactive Compounds and Essential Oils: A Review

et al. 2021

View full text Add to dashboard Cite

In recent years, liposomes have gained increasing attention for their potential applications as drug delivery systems in the pharmaceutic, cosmetic and food industries. However, they have a tendency to aggregate and are sensitive to degradation caused by several factors, which may limit their effectiveness. A promising approach to improve liposomal stability is to modify liposomal surfaces by forming polymeric layers. Among natural polymers, chitosan has received great interest due to its biocompatibility and biodegradability. This review discussed the characteristics of this combined system, called chitosomes, in comparison to those of conventional liposomes. The coating of liposomes with chitosan or its derivatives improved liposome stability, provided sustained drug release and increased drug penetration across mucus layers. The mechanisms behind these results are highlighted in this paper. Alternative assembly of polyelectrolytes using alginate, sodium hyaluronate, or pectin with chitosan could further improve the liposomal characteristics. Chitosomal encapsulation could also ensure targeted delivery and boost the antimicrobial efficacy of essential oils (EOs). Moreover, chitosomes could be an efficient tool to overcome the major drawbacks related to the chemical properties of EOs (low water solubility, sensitivity to oxygen, light, heat, and humidity) and their poor bioavailability. Overall, chitosomes could be considered as a promising strategy to enlarge the use of liposomes.

show abstract

Section: Encapsulation Of Essential Oils: Chitosomes Vs Liposomes Nmentioning

confidence: 99%

Chitosan-Coating Effect on the Characteristics of Liposomes: A Focus on Bioactive Compounds and Essential Oils: A Review

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Liposomes are typically comprised of phospholipids organized into bilayer structures [63]. Commonly, they contain one or more bilayers that are organized into concentric rings (Figure 3).…”

Section: Liposomesmentioning

confidence: 99%

Encapsulation and Protection of Omega-3-Rich Fish Oils Using Food-Grade Delivery Systems

Venugopalan

Gopakumar

Kumaran

et al. 2021

Foods

View full text Add to dashboard Cite

Regular consumption of adequate quantities of lipids rich in omega-3 fatty acids is claimed to provide a broad spectrum of health benefits, such as inhibiting inflammation, cardiovascular diseases, diabetes, arthritis, and ulcerative colitis. Lipids isolated from many marine sources are a rich source of long-chain polyunsaturated fatty acids (PUFAs) in the omega-3 form which are claimed to have particularly high biological activities. Functional food products designed to enhance human health and wellbeing are increasingly being fortified with these omega-3 PUFAs because of their potential nutritional and health benefits. However, food fortification with PUFAs is challenging because of their low water-solubility, their tendency to rapidly oxidize, and their variable bioavailability. These challenges can be addressed using advanced encapsulation technologies, which typically involve incorporating the omega-3 oils into well-designed colloidal particles fabricated from food-grade ingredients, such as liposomes, emulsion droplets, nanostructured lipid carriers, or microgels. These omega-3-enriched colloidal dispersions can be used in a fluid form or they can be converted into a powdered form using spray-drying, which facilitates their handling and storage, as well as prolonging their shelf life. In this review, we provide an overview of marine-based omega-3 fatty acid sources, discuss their health benefits, highlight the challenges involved with their utilization in functional foods, and present the different encapsulation technologies that can be used to improve their performance.

show abstract

“…Cholesterol is sometimes added to the membranes of the liposomes for the purpose of increasing their stability and the rigidity of the lipid bilayer, reducing their permeability and inhibition of phospholipid acyl chain crystallization by modulating the bilayer fluidity. Phytosterols have been recently used as a substitute of cholesterol in the formulation of liposomes since cholesterol may cause health problems especially for consumers who are suffering from hypercholesterolemia [24].…”

Section: Lipid Based Carriersmentioning

confidence: 99%

Lipid Based Drug Delivery System: A Review

Zubair

Sheshe

Bashir

et al. 2021

JALSI

View full text Add to dashboard Cite

Associated with the old/traditional of method of drug delivery are several limitation ranging from first-pass effect, low tolerance, minimal bioavailability, fluctuation of plasma drug concentration which result to less or no desired effect produced. This call for the demand for a more efficient drug administration technique. Lipid systems are biocompatible, inert and biodegradable, stable and deliver at the target with the desired effect. This paper attempt to describe several types of lipid particles used to deliver drug compounds and their applications as therapeutic agent in treating different clinical condition.

show abstract

Recent advances in food colloidal delivery systems for essential oils and their main components

Cited by 111 publications

References 98 publications

Chitosan-Coating Effect on the Characteristics of Liposomes: A Focus on Bioactive Compounds and Essential Oils: A Review

Chitosan-Coating Effect on the Characteristics of Liposomes: A Focus on Bioactive Compounds and Essential Oils: A Review

Encapsulation and Protection of Omega-3-Rich Fish Oils Using Food-Grade Delivery Systems

Lipid Based Drug Delivery System: A Review

Contact Info

Product

Resources

About