Recent Advancement of Biopolymers and Their Potential Biomedical Applications

Biswas, Manik Chandra; Jony, Bodiuzzaman; Nandy, Pranab K.; Chowdhury, Raqib; Halder, Sudipta; Kumar, Deepak; Ramakrishna, Seeram; Hassan, Masud; Ahsan, Ariful; Hoque, Enamul; Imam, Muhammad A.

doi:10.1007/s10924-021-02199-y

Cited by 79 publications

(34 citation statements)

References 194 publications

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“…Biomedical applications including drug delivery, tissue engineering, medical devices, pharmaceutical carriers, and wound healing are a much-prioritized field of research as one of the basic requirements of human society. [113][114][115][116] Last decades, researchers have emphasized their great attention to the versatile subsectors of biomedical research by using biopolymer nanocomposites due to the existing properties of biobased materials. Among biopolymers, the gelatin was applied in pharma products for wound dressing because of their properties like adhesion.…”

Section: Biopolymer For Biomedical Applicationsmentioning

confidence: 99%

Versatile Applications Of Biopolymer Nanocomposites: A review

et al. 2022

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Biopolymers having biodegradable and biocompatible characteristics have been gained a great interest of scientists for using various applications in the field of advanced sciences exclusively with nanotechnology of separation and purification field. Different exciting applications have been found in the versatile field including energy production, wastewater treatment, sensor development, food packaging and broadly in the biomedical sciences. Biopolymer can be applied to increase the capabilities of other bio‐active molecules in a material. Now dyes, scientists are concentrated for preparing more environment friendly nanomaterials and increasing attention for immobilizing of contaminates and adoption by using green chemistry approaches. This review has been summarized the vital applications of biopolymer and highlighted with their owned advantages and limitations of numerous field by reported studies. The possible mechanistic insights of diverse applications of biopolymers were discussed. This review has been finds the efficiencies of biopolymers in the major field of sciences and were considered as the outstanding materials due to their exciting physic‐chemical properties and other characteristics include eco‐friendly nature, low cost, nontoxic, high adsorption capacity and reusability. This review could be considered as a precious pathway for exploring more low‐cost, environmental friendly hybrid materials for versatile applications including water decontamination, sensing of targeted elements and other biomedical purposes, eventually the review will contribute to environmental remediation and purification applications of biomaterials.

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Section: Biopolymer For Biomedical Applicationsmentioning

confidence: 99%

Versatile Applications Of Biopolymer Nanocomposites: A review

et al. 2022

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“…The in vitro examinations of NIH-3T3 fibroblast cells that interacted with the HA revealed a good cell interaction, cell attachment, growth of cells, and non-toxicity. The in vitro studies proved that HA from snail shells has good biocompatibility (cell viability more than 90%) with no cytotoxicity [ 35 ].…”

Section: Biocompatibility Studymentioning

confidence: 99%

Fabrication, Characterization and In Vitro Assessment of Laevistrombus canarium-Derived Hydroxyapatite Particulate-Filled Polymer Composite for Implant Applications

Chinnappan¹,

Krishnaveni²,

Thanigachalam³

et al. 2022

Polymers

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This paper presents the formulation, characterization, and in vitro studies of polymer composite material impregnated with naturally derived hydroxyapatite (HA) particulates for biomedical implant applications. Laevistrombus canarium (LC) seashells (SS) were collected, washed and cleaned, sun-dried for 24 h, and ground into powder particulates. The SS particulates of different weight percentages (0, 10, 20, 30, 40, 50 wt%)-loaded high-density polyethylene (HDPE) composites were fabricated by compression molding for comparative in vitro assessment. A temperature-controlled compression molding technique was used with the operating pressure of 2 to 3 bars for particulate retention in the HDPE matrix during molding. The HDPE/LC composite was fabricated and characterized using X-ray diffraction (XRD), field-emission scanning electron microscopy (FESEM), energy-dispersive X-ray (EDX), differential scanning calorimetry (DSC), and TGA. Mechanical properties such as tensile, compression, flexural, hardness, and also surface roughness were tested as per ASTM standards. Mass degradation and thermal stability of the HDPE/LC composite were evaluated at different temperatures ranging from 10 to 700 °C using thermogravimetric analysis (TGA). The maximum tensile strength was found to be 27 ± 0.5 MPa for 30 wt% HDPE/LC composite. The thermal energy absorbed during endothermic processes was recorded as 71.24 J/g and the peak melting temperature (Tm) was found to be 128.4 °C for the same 30 wt% of HDPE/LC composite specimen. Excellent cell viability was observed during the in vitro biocompatibility study for EtO-sterilized 30 wt% of HDPE/LC composite specimen, except for a report of mild cytotoxicity in the case of higher concentration (50 µL) of the MG-63 cell line. The results demonstrate the potential of the fabricated composite as a suitable biomaterial for medical implant applications.

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“…[8] Biopolymers have been extensively used in the food industries, biomaterials, energy materials, nanodevices, and adsorption materials due to their inexpensiveness, availability, renewability, biodegradability, and biocompatibility. [9][10][11][12][13][14][15] Recently, researchers have noticed that the electrodeposition of biopolymers (e.g., chitosan, and alginate) can effectively combine microelectronics and biotechnology to create novel bioelectronic devices (e.g., biosensors, and biochips) and functional materials (e.g., antibacterial coatings). [16] It is noteworthy that our group developed a coordinated electrodeposition for biopolymers based on the coordination of biopolymers (e.g., chitosan) with metal ions (e.g., Ag + ) generated by electrochemical oxidation during the electrodeposition.…”

Section: Introductionmentioning

confidence: 99%

Electrodeposited Alginate‐Based Green Synthesis of CuS Nanoparticles and Nanocomposite Films for Electrochemical and Colorimetric Detection

Wang

Liu

et al. 2022

Macro Materials & Eng

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CuS nanoparticles (NPs) and CuS NPs/alginate nanocomposite films are prepared using a novel method based on the coordinated electrodeposition of alginate. This method exquisitely utilizes the coordination of alginate with Cu 2+ ions to carry out the electrodeposition, and alginate as the stabilizer for CuS NPs and the major ingredient in the nanocomposite film. Thus, the method has many advantages such as facile operation, green route, mild conditions, and convenient post-treatment. After the electrodeposition, a smooth and homogeneous film has been electrodeposited on the anodic electrode. Transmission electron microscopy observation reveals that there are nanoparticles (the average size of 6.0 nm) in the electrodeposited film. The results from spectral analysis further confirm the existence of CuS NPs. The CuS NPs/alginate nanocomposite film modified electrode can be directly constructed by taking advantage of the electrodeposition, which shows the electrochemical detection capability towards H 2 O 2 and hydroquinone. The CuS NPs/alginate nanocomposite film also possesses the colorimetric detection capability toward H 2 O 2 and dopamine. Therefore, this study offers a green and convenient method for fabricating CuS NPs and nanocomposite films, which is promising for applications in functional nanocomposites and detection fields.

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Recent Advancement of Biopolymers and Their Potential Biomedical Applications

Cited by 79 publications

References 194 publications

Versatile Applications Of Biopolymer Nanocomposites: A review

Versatile Applications Of Biopolymer Nanocomposites: A review

Fabrication, Characterization and In Vitro Assessment of Laevistrombus canarium-Derived Hydroxyapatite Particulate-Filled Polymer Composite for Implant Applications

Electrodeposited Alginate‐Based Green Synthesis of CuS Nanoparticles and Nanocomposite Films for Electrochemical and Colorimetric Detection

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