Recent Achievements in Electrochemical and Surface Plasmon Resonance Aptasensors for Mycotoxins Detection

Abstract

Mycotoxins are secondary metabolites of fungi that contaminate agriculture products. Their release in the environment can cause severe damage to human health. Aptasensors are compact analytical devices that are intended for the fast and reliable detection of various species able to specifically interact with aptamers attached to the transducer surface. In this review, assembly of electrochemical and surface plasmon resonance (SPR) aptasensors are considered with emphasis on the mechanism of signal generation. Moreover, the properties of mycotoxins and the aptamers selected for their recognition are briefly considered. The analytical performance of biosensors developed within last three years makes it possible to determine mycotoxin residues in water and agriculture/food products on the levels below their maximal admissible concentrations. Requirements for the development of sample treatment and future trends in aptasensors are also discussed.

Label-free electrochemical aptasensor for rapid detection of SARS-CoV-2 spike glycoprotein based on the composite of Cu(OH)2 nanorods arrays as a high-performance surface substrate

“…Different types of aptamer sensors (aptasensor) have been developed based on various transducers, including: electrochemical methods, surface plasmon resonance, colorimetric approach, fluorescence spectroscopy, optical transducers, etc. [28] , [29] , [30] , [31] , [32] . Among these techniques, electrochemical methods have received many attentions due to their innate high sensitivity, fast response times, real-time monitoring, simplicity, cost effectiveness, small sample amount requirement, low detection limits, amenability to miniaturization, etc.…”

Recent Advances in Recognition Receptors for Electrochemical Biosensing of Mycotoxins—A Review

“…Figure 2 shows four different immobilization methodologies. As per the driving forces of the process, immobilization could be classified into three groups, i.e., covalent, physical, and affinity immobilization [ 31 ].…”

Recent advances in immunoassay-based mycotoxin analysis and toxicogenomic technologies

“…EC immunosensor provides reliable quantitative results at low cost of assay and equipment. However, EC immunosensor is sensitive towards pH, ions and temperature of the samples [ 71 ]. Therefore, such factors should be taken into account during mycotoxin quantification.…”