Reassessment of osteoporosis-related femoral fractures and economic burden in Saudi Arabia

Sadat-Ali, Mir; Al-Dakheel, Dakheel A.; Azam, Quamar; Al-Bluwi, Mohammed T.; Alfarhan, Mohammed; AlAmer, Hussein A.; Al-Meer, Zakaria S.; Al-Mohimeed, Abdallah; Tabash, Ibrahim K.; Karry, Maher O.; Rassasy, Yaseen M.; Baragaba, Mohammed A.; Amer, Ahmed Sh.; AlJawder, Abdallah; Al-Bouri, Kamil M.; ElTinay, Mohammed; Badawi, Hamed A.; Al-Othman, Abdallah A.; Tayara, Badar K; Al-Faraidy, Moaad H.; Amin, Ahmed

doi:10.1007/s11657-015-0240-5

Cited by 31 publications

(27 citation statements)

References 13 publications

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“…Osteoporosis along with osteopenia is responsible for fragility fractures, which contribute to the increasing morbidity and mortality rates. A previous study published in 2015 showed that the proximal femoral fracture incidence is 5.89 per 1000 individuals, and the estimated lifetime spending for fragility femoral fractures was 9.34 billion USD [29–31]. Moreover, 17 billion USD was the total healthcare cost of two million cases of fractures in the USA alone, and such cost is calculated to increase to 25 billion USD in 2025 because of an estimated 50% increase in fracture incidence [32].…”

Section: Introductionmentioning

confidence: 99%

Relationship between Body Mass Index and T-Scores of Bone Mineral Density in the Hip and Spine Regions among Older Adults with Diabetes: A Retrospective Review

et al. 2019

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Diabetes mellitus (DM) cases are increasing worldwide, especially in Saudi Arabia. Previous studies suggested a positive relationship between body mass index (BMI) and bone mineral density (BMD) levels. Generally, patients with low BMI (<18.5 kg/m2) have reduced BMD levels and, thus, low T-scores; hence, they are categorized as osteopenic or osteoporotic. In this study, we aimed to determine whether a relationship between BMI and BMD T-scores in the hip and spine regions of patients with diabetes exists. This retrospective record review investigated older adult patients with diabetes in King Abdulaziz University Hospital (n=198; age 50–90 years) who underwent BMD scan between January 1, 2016, and June 25, 2018, regardless of their sex but limited to type 2 DM. The height and weight of all subjects were recorded, and BMI was calculated and categorized. We used SPSS version 21 for data analysis; measures of central tendencies, Pearson’s correlations, chi-square tests, and independent t-tests were employed. We found positive relationships between BMI and BMD T-scores in the hip and spine regions (right femoral neck: R=+0.214, P≤0.002; total right hip: R=+0.912, P≤0.001; left femoral neck: R=+0.939, P≤0.001; total left hip: R=+0.885, P≤0.001; and total lumbar region: R=+0.607, P≤0.001). Low BMI (<18.5 kg/m2) could be a risk factor for osteoporosis, whereas normal/high BMI could be protective against osteoporosis among adults with diabetes.

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Section: Introductionmentioning

confidence: 99%

Relationship between Body Mass Index and T-Scores of Bone Mineral Density in the Hip and Spine Regions among Older Adults with Diabetes: A Retrospective Review

et al. 2019

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“… 6 , 7 A recent study revealed that the incidence of proximal femoral fractures in a Saudi population of patients aged ≥50 years was 5.89/1000. 8 Very high mortality rates associated with fragility hip fractures have been reported in developed countries, with 5% to 10% of affecting patients dying within 1 month of fracture and 20% to 30% dying within 1 year. 9 , 10 In 2013, Diamantopoulos et al.…”

Section: Introductionmentioning

confidence: 99%

Morbidity and mortality after fragility hip fracture in a Saudi Arabian population: Report from a single center

et al. 2017

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ObjectiveTo determine the functional morbidity and mortality after fragility hip fracture and compare the mortality with three other common diseases.MethodsData were collected from patients admitted to King Fahd Hospital of the University, AlKhobar from January 2010 to December 2014. Demographic data included the preoperative American Society of Anesthesiologists (ASA) score as assessed by the anesthetist and the type of surgery. Personal and telephone interviews were performed, and data were entered into a database and analyzed.ResultsWe identified 203 patients with fragility proximal femoral fractures, and the data of 189 patients (109 male, 80 female; average age, 66.90 ± 13.43 years) were available for analysis. The overall mortality rate was 26.98% (51 patients). The mortality rate was significantly higher among patients with an ASA score of 4 (36.36%) than 1 (20.45%). With respect to morbidity, only 48.23% of patients were able to return to their pre-fracture status; 32.35% of those who required assisted walking and 83.4% of those who required a wheelchair became bedridden.ConclusionsOur data demonstrate that patients with fragility hip fractures have high morbidity and a mortality rate approaching 30%. Age and the ASA score significantly influence this high mortality rate.

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“…[ 5 ] It was reported that direct and indirect costs of osteoporosis-related hip fractures yearly in Saudi Arabia reached Saudi riyals 2.359 billion and is projected that the lifetime costs of this single osteoporosis-related hip fracture by 2025 will reach SR35.0028 billion ($9.34 billion). [ 8 ] If the patients are screened earlier and treated appropriately as per the US database of 2011, it will cost $2 billion, and if left untreated, once the fragility fractures are treated, the cost goes eight times to $16 billion. [ 14 ]…”

Section: Discussionmentioning

confidence: 99%

“…[ 6 ] In Saudi Arabia, a neighbor of the Kingdom of Bahrain, the incidence of fractures rose from 2.9/1000 of the population in Riyadh[ 7 ] to 5.8/1000 in the Eastern Province. [ 8 ]…”

Section: Introductionmentioning

confidence: 99%

Osteoporosis among bahraini citizens: The first report

Sadat-Ali

Mattar

2020

Int J App Basic Med Res

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Reassessment of osteoporosis-related femoral fractures and economic burden in Saudi Arabia

Cited by 31 publications

References 13 publications

Relationship between Body Mass Index and T-Scores of Bone Mineral Density in the Hip and Spine Regions among Older Adults with Diabetes: A Retrospective Review

Relationship between Body Mass Index and T-Scores of Bone Mineral Density in the Hip and Spine Regions among Older Adults with Diabetes: A Retrospective Review

Morbidity and mortality after fragility hip fracture in a Saudi Arabian population: Report from a single center

Osteoporosis among bahraini citizens: The first report

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