Realization of a Double-Exposure Interferometer with Photorefractive Crystals for Biomedical Applications

Weber, M.; Rickermann, F.; Bally, Gert von

doi:10.1007/978-3-642-56965-4_61

Cited by 2 publications

(4 citation statements)

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“…The holographic interferometry using the photorefractive crystals as recording medium is called photorefractive holographic interferometry (Weber et al, 1999;Gunter and Huinard, 1998;Kamshilin and Petrov, 1985;Gesualdi et al, 2006aGesualdi et al, , 2006bBarbosa et al, 2007). In this case, we use a Bi 12 SiO 20 (BSO) sillenite crystal (with transverse electro-optic configuration and dimensions 10 Â 10 Â 3 mm 3 ) as recording holographic medium in a double-exposure holographic interferometry: 2E-PRHI setup, showed in Fig.…”

Section: Double-exposure Holographic Interferometry (2ehi)mentioning

confidence: 97%

“…Those techniques present important advantages over the conventional ones: they do not present any contact with the studied surfaces, providing high reliability and accuracy of quantitative and qualitative analysis through visual inspection on vibration analysis, strain and deformation measurements. Moreover, for medical research one series of works had been carried through using the optic and holographic interferometry techniques for biomechanics analysis of the cranium facial complex, superficial micro-displacements of bone structures, sutures composed, medullar bone, cortical bone and dentoalveolar articulation (Ovryn, 1989;Pryputniewicz, 1979;Spetzles and Spetzler, 1980;Braun et al, 2000;Kragt et al, 1979;Weber et al, 1999;Savić -Šević and Pantelić , 2005;Banerjee et al, 2008;Bottlanga et al, 2008).…”

Section: Introductionmentioning

confidence: 99%

“…In this work, we have utilized the Photorefractive Holographic Interferometry (PRHI) (Weber et al, 1999;Gunter and Huinard, 1998;Kamshilin and Petrov, 1985;Gesualdi et al, 2006aGesualdi et al, , 2006bBarbosa et al, 2007), more specifically, the Double-Exposure Photorefractive Holographic Interferometry Technique (2E-PRHI) using Bi 12 SiO 20 (BSO) crystal, as recording medium (diffusion regimen), to analyse the surface micro-displacements by a Fringe Analysis Method (Robinson and Reid, 1993). It was utilized to record micro-displacements and to obtain force-displacement response in the bones structure from dried human skull during the Simulation of Isolated Contraction (SIC) of mastication muscles: ABLT (Anterior Branch of Left Temporalis muscle) and LDM (Left Deep Masseter muscle).…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Mastication effort study using photorefractive holographic interferometry technique

Caroena

Mori

Gesualdi

et al. 2010

Journal of Biomechanics

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Section: Double-exposure Holographic Interferometry (2ehi)mentioning

confidence: 97%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Mastication effort study using photorefractive holographic interferometry technique

Caroena

Mori

Gesualdi

et al. 2010

Journal of Biomechanics

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“…Photorefractive crystals have been proved to be high resolution recording materials for reversible storage of double exposure holographic interferograms [8]. To apply a holographic double exposure interferometer for investigations on cellular tissue and living cells a lateral resolution in microscopic dimensions in combination with high contrast reconstructed holographic images is required.…”

Section: Holographic Interferometric Microscopy With Photorefrative Rmentioning

confidence: 99%

Holographic interferometric microscopy systems for the application on biological samples

Kemper

Carl

Knoche

et al. 2004

Optical Metrology in Production Engineering

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Holographic interferometric metrology allows a fast, non destructive and quantitative high resolution full field detection of optical path length changes. Furthermore, by utilization of modern CCD sensor technology and digital image processing algorithms an on-line application of these methods even on biological specimens is possible. In combination with a microscopic resolution this offers new possibilities for the detection of variations of shape, micro movements or refractive index changes e. g. for the marker free analysis of cellular samples. Three holographic interferometric systems for microscopy applications based on digital holography, (speckle) interferometry and photorefractive crystals as holographic recording medium are introduced. Results of investigations on test charts and biological samples to characterize and optimize the lateral resolution as well as the resolution of the detected phase difference changes are presented and discussed. Finally, the applicability of the developed measurement techniques on living cells is demonstrated. INTRODUCTIONHolographic and speckle interferometry are well-established and frequently applied tools for non destructive testing (NDT) and the analysis of displacements, movements and vibrations. With a measurement accuracy in sub-micrometer range this methods have already been applied in many fields of industry [1] as well as for biomedical applications [2]. Furthermore, by utilization of modern CCD sensor technology and fast digital image processing an on-line application of these methods even in vivo [3] is possible. Holographic interferometric metrology allows a fast, non-contact and quantitative high resolution full field detection of optical path length changes. This offers in combination with a microscopic resolution new possibilities for the analysis of cellular tissues and cells. In the upcoming fields of life sciences and biophotonics there is a requirement for an optical instrumentation of timely and spatially high resolution analysis, measurement and documentation in microscopic dimensions. Here, applications are of particular interest to get enhanced information about cellular tissues and single cells e. g. the detection of shape variations and refractive index changes as well as the full field analysis of parameters like micro movements or the local distribution of elasticity. Up to the present, such parameters are in general not considered in cellular and sub cellular dimensions although they are already routinely used e. g. for defect detection and tumor diagnostics in the macroscopic scale. In that view, holographic interferometric microscopy tools open up new facilities for a marker free monitoring of life processes and cell manipulation as well as for an automated cell differentiation and feedback systems for growing processes in tissue engineering.For such applications of holographic interferometric metrology, the specific requirements for the analysis of cellular tissues and living cells have to be considered and a lateral resolution in microscop...

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Realization of a Double-Exposure Interferometer with Photorefractive Crystals for Biomedical Applications

Cited by 2 publications

References 4 publications

Mastication effort study using photorefractive holographic interferometry technique

Mastication effort study using photorefractive holographic interferometry technique

Holographic interferometric microscopy systems for the application on biological samples

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