Real-world safety and efficacy of ticagrelor in patients with ST segment elevation myocardial infarction at Assiut University Heart Hospital

A Case of Intraparenchymal Hepatic Hemorrhage Due to Ticagrelor Loading Treatment in an Elderly Patient With Acute Coronary Syndrome

“…However, rather than relying on any test in clinical practice, for reasons such as drug-related side effects (dyspnea, arrhythmia, etc. ), major and minor bleeding complications, newly started anticoagulant drugs, drug incompatibility or emerging clinical conditions such as previous stroke; de-escalation of potent antiaggregant to classical clopidogrel appears to be applied [ 8 ]. As a matter of fact, in our patient, de-escalation was applied to clopidogrel due to the major bleeding complication in hospitalization without any PFT or genetic testing.…”