Real-time multi-channel stimulus artifact suppression by local curve fitting

Wagenaar, Daniel A.; Potter, Steve M.

doi:10.1016/s0165-0270(02)00149-8

Cited by 212 publications

(182 citation statements)

References 27 publications

(31 reference statements)

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“…Data acquisition and online analysis, including visualization, artifact suppression, spike detection and storage were controlled through MeaBench . Artifact suppression was performed by subtracting third-order polynomials locally fitted to the recorded voltage trace, using the SALPA ('suppression of artifacts by local polynomial approximation') algorithm (Wagenaar and Potter 2002). A C++ implementation of this algorithm is available upon request from the authors.…”

Section: Recording Systemmentioning

confidence: 99%

“…This caused minor artifacts on the other channels: signals remained within the amplifier's dynamic range throughout the stimulus in >99% of trials, and the absolute value of the artifact 1 ms after the end of the stimulus was 10.6 ± 15.6 µV (mean ± SSD). These artifacts could be entirely suppressed in software using SALPA (Wagenaar and Potter 2002). The stimulated channel itself did record significant artifacts: in 55% of trials the signal was driven outside of the amplifier's dynamic range (±683 µV) for 10 ms or more.…”

Section: 23mentioning

confidence: 99%

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A versatile all-channel stimulator for electrode arrays, with real-time control

Wagenaar

Potter

2004

J. Neural Eng.

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Over the last few decades, technology to record through ever increasing numbers of electrodes has become available to electrophysiologists. For the study of distributed neural processing, however, the ability to stimulate through equal numbers of electrodes, and thus to attain bidirectional communication, is of paramount importance. Here, we present a stimulation system for multi-electrode arrays which interfaces with existing commercial recording hardware, and allows stimulation through any electrode in the array, with rapid switching between channels. The system is controlled through real-time Linux, making it extremely flexible: stimulation sequences can be constructed on-the-fly, and arbitrary stimulus waveforms can be used if desired. A key feature of this design is that it can be readily and inexpensively reproduced in other labs, since it interfaces to standard PC parallel ports and uses only off-the-shelf components. Moreover, adaptation for use with in vivo multi-electrode probes would be straightforward. In combination with our freely available data-acquisition software, MeaBench, this system can provide feedback stimulation in response to recorded action potentials within 15 ms.

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Section: Recording Systemmentioning

confidence: 99%

Section: 23mentioning

confidence: 99%

A versatile all-channel stimulator for electrode arrays, with real-time control

Wagenaar

Potter

2004

J. Neural Eng.

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“…This prevents the input amplifiers from saturating and improves the hardware performance. In [6], artifacts are by characterizing the artifact and then subtracting it from the overall recording. While this approach removes the artifact from the recordings, the hardware considerations involved with recording the high amplitude artifact are not ameliorated.…”

Section: Literature Reviewmentioning

confidence: 99%

Equalization for intracortical microstimulation artifact reduction

Chu

Muller

Koralek

et al. 2013

2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

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I present a method for decreasing the duration of artifacts present during intracortical microstimulation (ICMS) recordings by using techniques developed for digital communications. I use a Zero-Forcing Equalizer (ZFE) to shape a stimulus pattern with the aim of reducing artifact length. The results find that using the ZFE stimulus has the potential to reduce artifact duration by more than 70%. Continuing work and current considerations for the hardware implementation of the equalizer are presented.

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“…We delivered biphasic stimuli (monopolar) at 500 mV and 400 μs per phase by using our custom-made stimulator . Data acquisition, visualization, artifact suppression (Wagenaar and Potter 2002) and spike detection were performed using MultiChannel Systems hardware and our publicly available acquisition and analysis software, Meabench (Potter et al 2006). Experiments were conducted in an incubator to control environmental conditions.…”

Section: Experiments In Living Culturesmentioning

confidence: 99%

Region-specific network plasticity in simulated and living cortical networks: comparison of the center of activity trajectory (CAT) with other statistics

Chao

Bakkum²,

Potter³

2007

J. Neural Eng.

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Electrically interfaced cortical networks cultured in vitro can be used as a model for studying the network mechanisms of learning and memory. Lasting changes in functional connectivity have been difficult to detect with extracellular multi-electrode arrays using standard firing rate statistics. We used both simulated and living networks to compare the ability of various statistics to quantify functional plasticity at the network level. Using a simulated integrate-and-fire neural network, we compared five established statistical methods to one of our own design, called center of activity trajectory (CAT). CAT, which depicts dynamics of the location-weighted average of spatiotemporal patterns of action potentials across the physical space of the neuronal circuitry, was the most sensitive statistic for detecting tetanus-induced plasticity in both simulated and living networks. By reducing the dimensionality of multi-unit data while still including spatial information, CAT allows efficient real-time computation of spatiotemporal activity patterns. Thus, CAT will be useful for studies in vivo or in vitro in which the locations of recording sites on multi-electrode probes are important.

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Real-time multi-channel stimulus artifact suppression by local curve fitting

Cited by 212 publications

References 27 publications

A versatile all-channel stimulator for electrode arrays, with real-time control

A versatile all-channel stimulator for electrode arrays, with real-time control

Equalization for intracortical microstimulation artifact reduction

Region-specific network plasticity in simulated and living cortical networks: comparison of the center of activity trajectory (CAT) with other statistics

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