Real-time and Doppler US after pediatric segmental liver transplantation

Suzuki, Lisa; Oliveira, Ilka Regina Souza de; Widman, Azzo; Gibeli, Nelson E. M.; Carnevale, Francisco César; Maksoud, João Gilberto; Hubbard, Anne M.; Cerri, Giovanni Guido

doi:10.1007/s00247-007-0731-7

Cited by 18 publications

(18 citation statements)

References 14 publications

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“…The rate of stenosis was 8.4% (Table 2). In 5 patients, fortunately, stenosis was detected early by ultrasonic studies and was treated with percutaneous balloon dilatation [26]. One patient with stenosis died while waiting for retransplantation.…”

Section: Discussionmentioning

confidence: 99%

Pediatric liver transplantation in Hong Kong—a domain with scarce deceased donors

Chan

Fan

et al. 2009

Journal of Pediatric Surgery

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Section: Discussionmentioning

confidence: 99%

Pediatric liver transplantation in Hong Kong—a domain with scarce deceased donors

Chan

Fan

et al. 2009

Journal of Pediatric Surgery

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“…Color Doppler US abnormalities were diagnosed when one or more of the following criteria were present in at least two consecutive examinations : hepatic artery—tardus‐parvus pattern, RI < 0.5 or >0.8, peak systolic velocity <30 cm/sec or peak focal systolic velocity >200 cm/sec, change in systolic peak velocity of >30% in comparison with previous investigations, and absence of arterial flow at the porta hepatis or at intraparenchymal level; portal vein—peak velocity <20 cm/sec, disproportional peak velocity in the portal vein compared with the splenic vein (peak portal velocity < peak splenic velocity), undulating or retrograde portal venous flow, or change in peak portal velocity > 30% in comparison with previous values; and hepatic veins—signs of hepatic outflow obstruction, loss of phasic waveform in follow‐up, and peak venous velocity >120 cm/sec.…”

Section: Methodsmentioning

confidence: 99%

Persistence of post‐operative color Doppler abnormalities is linked to reduced graft survival in pediatric patients after liver transplantation

Herrmann

Tozakidou

Busch

et al. 2019

Pediatric Transplantation

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Color Doppler US is a readily available imaging modality for the evaluation of liver transplants. The aim of our study was to evaluate the temporal course of color Doppler US findings in children after LTX and to investigate the effect of resolving and persisting abnormalities during follow‐up on long‐term outcome. All children who underwent LTX during January 2000 until December 2003 (155 LTX in 137 patients, 75 male and 62 female; mean age at LTX 4.1 ± 4.8 years; range, 0.1‐16.3 years) were retrospectively evaluated. Following a predefined ultrasound protocol with prospective documentation, intraoperative, post‐operative, and follow‐up examinations were evaluated for color Doppler abnormalities. The time of occurrence and temporal course of the findings were recorded. Graft survival rates and graft survival times were compared. Abnormal color Doppler US examinations were noted in 98 of 155 grafts during the entire observational period (63.2%). In 57 of 98 grafts (58.2%), abnormalities were limited to the perioperative period (<30 days after LTX). Survival of grafts with transient perioperative abnormalities was similar to transplantations with regular color Doppler US examinations (graft survival rates, 80.7% vs 84.2%, P = .622; mean graft survival time, 2596.92 vs 2511.40 days, P = .67). Grafts with persisting color Doppler US abnormalities in the follow‐up period (>30 days after LTX; 37/98 LTX, 37.8%) showed reduced survival compared with regular courses (graft survival rate 62.2% vs 80.7%, P = .047), indicating underlying organ‐specific alterations. Standardized longitudinal evaluation during the perioperative and the follow‐up period can enhance the prognostic capabilities of color Doppler US in children following LTX.

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“…This system allowed us to accurately set the flow splits to simulate physiological (LHV/MHV/RHV: 0.4/0.4/0.2) and pathological flow rates (LHV/MHV/RHV: 0.3/0.4/0.2) reported in literature. [27][28][29]48,69,72 The experimental flow conditions are tabulated in Table 1. These flow conditions are labeled ''healthy'' and ''pathological'' according to the clinical diagnoses of pediatric patients.…”

Section: In Vitro Flow Loopmentioning

confidence: 99%

Hemodynamics of the Hepatic Venous Three-Vessel Confluences Using Particle Image Velocimetry

et al. 2011

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Despite rapid advancements in the patient-specific hemodynamic analysis of systemic arterial anatomies, limited attention has been given to the characterization of major venous flow components, such as the hepatic venous confluence. A detailed investigation of hepatic flow structures is essential to better understand the origin of characteristic abnormal venous flow patterns observed in patients with cardiovascular venous disease. The present study incorporates transparent rapid-prototype replicas of two pediatric hepatic venous confluence anatomies and two-component particle image velocimetry to investigate the primary flow structures influencing the inferior vena cava outflow. Novel jet flow regimes are reported at physiologically relevant mean venous conditions. The sensitivity of fluid unsteadiness and hydraulic resistance to multiple-inlet flow regimes is documented. Pressure drop measurements, jet flow characterization, and blood damage assessments are also performed. Results indicate that the orientation of the inlets significantly influences the major unsteady flow structures and power loss characteristics of this complex venous flow junction. Compared to out-of-plane arranged inlet vessel configuration, the internal flow field observed in planar inlet configurations was less sensitive to the venous inlet flow split. Under pathological flow conditions, the effective pressure drop increased as much as 77% compared to the healthy flow state. Experimental flow field results presented here can serve as a benchmark case for the surgical optimization of complex anatomical confluences including visceral hemodynamics as well as for the experimental validation of high-resolution computational fluid dynamics solvers applied to anatomical confluences with multiple inlets and outlets.

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Real-time and Doppler US after pediatric segmental liver transplantation

Abstract: An HV1/HV2 ratio of >4.1 is a highly predictive CD-US parameter for the detection of hemodynamically significant HV stenosis on angiography.

Cited by 18 publications

References 14 publications

Pediatric liver transplantation in Hong Kong—a domain with scarce deceased donors

Pediatric liver transplantation in Hong Kong—a domain with scarce deceased donors

Persistence of post‐operative color Doppler abnormalities is linked to reduced graft survival in pediatric patients after liver transplantation

Hemodynamics of the Hepatic Venous Three-Vessel Confluences Using Particle Image Velocimetry

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