Reactive Pericarditis post Meningococcal Vaccine: First Case Report in the Literature

Al-Ebrahim, Ebrahim Khalid; Algazzar, Alaa Solaiman; Qutub, Mohammed

doi:10.36660/ijcs.20200064

Cited by 4 publications

(3 citation statements)

References 12 publications

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“…Perimyocarditis as an adverse event was studied along the years as published literature includes numerous case reports following inoculation with various vaccines in both adults and children. 18–20 No specific risk factors were suggested in those case reports, nor was a clear mechanism suggested. Historically, smallpox vaccines were reported to be associated with a significant number of cases of perimyocarditis in both first-time vaccines and after recurrent doses.…”

Section: Discussionmentioning

confidence: 94%

Transient Cardiac Injury in Adolescents Receiving the BNT162b2 mRNA COVID-19 Vaccine

Snapiri¹,

Danziger²,

Shirman³

et al. 2021

Pediatric Infectious Disease Journal

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Background: Vaccines are paramount in the effort to end the coronavirus disease 2019 global epidemic. BNT162b2 is approved for the vaccination of adolescents over 16 years of age. Systemic adverse events were scarce though the pretested cohort of this age group was relatively small. The aim of the current study is to raise awareness for potential adverse reactions. Methods: This is a case series of patients diagnosed with perimyocarditis following vaccination. Patients were compiled from 3 pediatric medical centers in Israel through a network of pediatricians and data regarding those cases was collected. In addition, incidence of perimyocarditis during the vaccination period was compared with previous years. Results: All patients were males 16–18 years old, of Jewish descent, who presented with chest pain that began 1–3 days following vaccination (mean, 2.1 days). In 6 of the 7 patients, symptoms began following the 2nd dose and in 1 patient following the 1st dose. All cases were mild and none required cardiovascular or respiratory support. The incidence of perimyocarditis during the vaccination period was elevated in comparison to previous years. Conclusions: This case series describes a time association between coronavirus disease 2019 vaccine and perimyocarditis in adolescents. All cases were mild, although only long-term follow-up can reveal the true impact of this cardiac injury. While it seems that the incidence of perimyocarditis during the vaccination campaign period is increased, a more comprehensive data collection on a wider scale should be done. We hope this report will serve as a reminder to report events and allow for analysis of potential adverse reactions.

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Section: Discussionmentioning

confidence: 94%

Transient Cardiac Injury in Adolescents Receiving the BNT162b2 mRNA COVID-19 Vaccine

Snapiri¹,

Danziger²,

Shirman³

et al. 2021

Pediatric Infectious Disease Journal

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“…Pericarditis may occur following COVID-19 vaccination, both as new-onset pericarditis or a recurrent flare in patients with prior episodes. This phenomenon is rarely associated with other vaccines, except following meningococcal and live vaccines, such as the smallpox vaccine [83][84][85]. On the other hand, recurrent pericarditis had previously been reported after influenza vaccination.…”

Section: Covid-19 Vaccine-associated Myocarditismentioning

confidence: 98%

Myocarditis and Pericarditis Following the SARS-CoV-2 Infection and COVID-19 Vaccination

Afshar¹,

Liang²,

Habib³

et al. 2023

Preprint

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Cardiac complications of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection have been well-identified since the beginning of the current coronavirus disease 2019 (COVID-19) pandemic. Such conditions can occur of various etiologies, such as respiratory failure and hypoxemia, direct cardiac tissue damage due to viral replication, indirect myocarditis as systemic inflammation, and the interaction of different medications. Recently, with the start of the COVID-19 vaccination programs, COVID-19 vaccine-associated cardiac adverse events (AEs) have emerged and are increasingly being reported. Although these AEs are usually mild and self-limited, they can sometimes cause severe, catastrophic outcomes. This review compares the pathophysiology, diagnosis, and treatment of the de novo SARS-CoV-2 infection-related and COVID-19 vaccine-related myocarditis and pericarditis.

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“…A case report of a 22-year-old male developed reactive pericarditis 5 days post vaccination (Meningococcal groups A, C, W-135, and Y conjugate vaccine). After testing for other causes of pericarditis, vaccine-induced pericarditis was diagnosed ( Al-Ebrahim et al, 2020 ) [A].…”

Section: Bacterial Vaccinesmentioning

confidence: 99%

Vaccines

Ambler

Towne

Brooks

2021

Side Effects of Drugs Annual

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Reactive Pericarditis post Meningococcal Vaccine: First Case Report in the Literature

Cited by 4 publications

References 12 publications

Transient Cardiac Injury in Adolescents Receiving the BNT162b2 mRNA COVID-19 Vaccine

Transient Cardiac Injury in Adolescents Receiving the BNT162b2 mRNA COVID-19 Vaccine

Myocarditis and Pericarditis Following the SARS-CoV-2 Infection and COVID-19 Vaccination

Vaccines

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