Reaction of the Rat Omentum to Injections of Particulate Matter

Abstract

REACTION OF RAT OMENTUM TO PARTICULATE MATTER 409apparently gave some immunity in the vaccinated group at institution Y, but none at X. V-2 produced a slightly, but perhaps not significantly, greater antibody-response than did V-1 , as judged by complement-fixation and neutralization-tests. It is quite probable that subclinical infections accounted for some of the increase in antibodies. It also appeared that the response in complement-fixing antibodies produced by the two vaccines was considerably less in degree than the response following infection. Swnzmary. Studies were conducted at two large institutions during an outbreak of influenza A which was proven by complementfixation tests. Persons at both institutions received a living virus and complex forrnalinized vaccine previous to the outbreak. An epidemiological survey revealed some protection at one institution, but none at the other. There was no obvious difference in the prophylactic efficacy of the two vaccines in the relatively small group of 829 individuals studied.

The milky spots of the peritoneum and pleura: structure, development and pathology

“…A decreased quantity of adipocytes is observed due to retransformation of "inactive" MS fat nodes in "active" secondary MS (52,(125)(126)(127)(128). There is mobilization of the fixed mesenchymal cells in the active MS (52,129), and transformation of these cells in active phagocytes and macrophages that migrate towards the surface of the MS (2,129). They concentrate under the serous covering and phagocytise the foreign material (129).…”

“…There is mobilization of the fixed mesenchymal cells in the active MS (52,129), and transformation of these cells in active phagocytes and macrophages that migrate towards the surface of the MS (2,129). They concentrate under the serous covering and phagocytise the foreign material (129). Certain particles of foreign material remain encapsulated in the omental MS forever (2,130,131).…”

“…MS appear appropriate as a target organ in every phase of tumor cell metastasis (19,(159)(160)(161)(162). Cancer cells usually form clumps in the ascitic fluid (163), and have a high chance of attaching to the omentum because omentum takes part in fluid drainage from the peritoneal cavity (2,5,9,19,129,(164)(165)(166). Exfoliation of mesothelial cells and basal lamina degradation appear to be essential steps for tumor cell infiltration (167,168).…”