Reaction of cefalexine with manganese(II), cobalt(II), nickel(II), zinc(II), and cadmium(II) ions

Алексеев, В. Г.; Никифорова, А. А.; Markelova, SV

doi:10.1134/s1070363206090192

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Introduction1

Loading and In Vitro Release Of Cephalexin1

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2014

2024

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Cited by 7 publications

(2 citation statements)

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“…The molecule (HCpx) contains NH 2 , C(O)NH, and C(O)OH groups, so it is similar in structure and acid-base properties to dipeptide molecules. Depending on the pH, cephalexin molecules exist in aqueous solution as positively charged H 2 Cpx + species, as HCpx − zwitterions, or as Cpx − , anionic, negatively charged entities [2].…”

Section: Introductionmentioning

confidence: 99%

Influence of pH on cephalexin adsorption onto SBA-15 mesoporous silica: Theoretical and experimental study

Legnoverde

Simonetti

Basaldella

2014

Applied Surface Science

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Section: Introductionmentioning

confidence: 99%

Influence of pH on cephalexin adsorption onto SBA-15 mesoporous silica: Theoretical and experimental study

Legnoverde

Simonetti

Basaldella

2014

Applied Surface Science

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“…The presence of -COOH, -CONH, -NH 2 moieties in the Cephalexin molecule and its inherent acid-base properties resemble to the dipeptide molecule. Depending upon the pH of aqueous medium, Cephalexin (denoted as CPX) can exist as cation (H 2 CPX þ ), zwitterion (HCPX À ) and anion (CPX À ) [31]. The zwitterion form of Cephalexin dominates within a pH range of 2.56-6.88 [32].…”

Section: Loading and In Vitro Release Of Cephalexinmentioning

confidence: 99%

Development of microcrystalline cellulose based hydrogels for the in vitro delivery of Cephalexin

Kundu

Banerjee

2020

Heliyon

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Three hydrogels namely, microcrystalline cellulose (MCC), microcrystalline cellulose-carboxymethyl cellulose (MCC-CMC) and microcrystalline cellulose-xylan (MCC-xylan) are synthesized using ethylene glycol diglycidyl ether as crosslinker. For the chemical characterization, FT-IR spectroscopy is adopted, whereas gel fraction and swelling ratio are used for the physical characterization of the hydrogels. Coarse morphology of hydrogels is further visualized by microscopic observation. The rheological characterization proves that MCC-CMC gel withstands higher strain to resist permanent deformation than the other two gels. The hydrogels are used for the loading and in vitro release of Cephalexin. The in vitro delivery is carried out in various simulated body fluids such as phosphate buffer saline (PBS), artificial intestinal fluid (AIF) and artificial gastric fluid (AGF). MCC-CMC is observed to deliver Cephalexin individually

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Adsorption of cephalexin in aqueous media by graphene oxide: kinetics, isotherm, and thermodynamics

Wernke

Shimabuku‐Biadola

Santos

et al. 2019

Environ Sci Pollut Res

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Reaction of cefalexine with manganese(II), cobalt(II), nickel(II), zinc(II), and cadmium(II) ions

Cited by 7 publications

References 5 publications

Influence of pH on cephalexin adsorption onto SBA-15 mesoporous silica: Theoretical and experimental study

Influence of pH on cephalexin adsorption onto SBA-15 mesoporous silica: Theoretical and experimental study

Development of microcrystalline cellulose based hydrogels for the in vitro delivery of Cephalexin

Adsorption of cephalexin in aqueous media by graphene oxide: kinetics, isotherm, and thermodynamics

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