Reaction of 1‐formyladamantane with heterocyclic compounds. Mass spectra, antibacterial and antifungal activity

G, Fenech; Monforte, P; Chimirri, Alba; Grasso, Silvana

doi:10.1002/jhet.5570160229

Cited by 11 publications

(6 citation statements)

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“…On the other hand, 5-arylazo-4thiono-2-thiazolidinones (129) give both Nand Smethylated derivatives, 130 and 131, respectively, when treated with ethereal diazomethane.176 5-Arylidene-4-(arylimino)-2-thiazolidinones (132) yield iV-methyl derivatives (133) in the presence of ethereal diazomethane or methyl iodide and potassium ethoxide. 177 Compound 125 undergoes Mannich reaction176 and gives N-alkylated derivatives (134). Furthermore, the…”

Section: -Thiazolidinonesmentioning

confidence: 99%

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Chemistry and biological activity of thiazolidinones

Singh¹,

Parmar²,

Raman³

et al. 1981

Chem. Rev.

396

183

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Section: -Thiazolidinonesmentioning

confidence: 99%

“…The imino-amino tautomerism of 2-imino-4-thiazolidinones and its derivatives was studied by infrared nc6h5 ArHC A and 4-thiazolidinones have been reported by other workers (ref 105,110,119,123,134,[149][150][151]164,176,179,184,225,258,259,[264][265][266][267].…”

Section: B Infrared Spectroscopymentioning

confidence: 99%

Chemistry and biological activity of thiazolidinones

Singh¹,

Parmar²,

Raman³

et al. 1981

Chem. Rev.

396

183

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“…+ was found to be as base peak. Radical ion [c] + exhibited CH-S bond cleavage (b-cleavage) followed by a rearrangement through a 1,4-hydrogen shift leading to the formation of ion [f] + at m/z 208 (loss of SCHCO) [14]. …”

Section: -{[(29-(299-substitutedaryl-499-thiazolidinon-399-yl)-1939mentioning

confidence: 99%

Synthesis of New Thiazolylthiazolidinylbenzothiazoles and Thiazolylazetidinylbenzothiazoles as Potential Insecticidal, Antifungal, and Antibacterial Agents

Singh

Srivastava

Saxena

et al. 2006

Archiv der Pharmazie

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A series of 2-{[2'-(3''-chloro-2''-oxo-4''-substitutedaryl-1''-azetidinyl)-1',3'-thiazol-4'-yl] thio}benzothiazoles (4a-4e) and 2-{[(2'-(2''-substitutedaryl-4''-thiazolidinon-3''-yl)-1',3'-thiazol-4'-yl]thio}benzothiazoles (5a-5e) have been synthesized from 2-[(2'-substitutedarylidenylimino-1',3'-thiazol-4'-yl)thio]benzothiazoles (3a-3e). The structure of these compounds has been elucidated by elemental (C, H, N) and spectral (IR, (1)H-NMR, Mass) analysis. Furthermore, compounds 3a-3e, 4a-4e, and 5a-5e were screened for insecticidal activity against Periplaneta americana and antifungal, antibacterial activities in vitro against different strains of fungi and bacteria. Out of the fifteen compounds tested, compound 5b, 2-{[2'-(2''-p-hydroxy-m-methoxyphenyl)-4''-thiazolidinon-3''-yl)-1',3'-thiazol-4'-yl]thio}benzothiazole, was found to possess most prominent insecticidal activity.

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“…This encouraged us to explore the synthesis of 3- O -acylides bearing other heterocyclic systems for example thiazolidinone in place of the pyridyl residue. The thiazolidinone functionality in the molecule may be advantageous for antibacterial activity in view of similar system having been reported as antibacterials [ 10 – 11 ]. The thiazolidin-4-ones can be generated under very mild conditions using the DCC mediated one-pot synthesis reported by us [ 12 ].…”

Section: Introductionmentioning

confidence: 99%