Reaction Engineering for Continuous Production of Silver Nanoparticles

Abstract

A scalable process for the production of silver nanoparticles that allows for complete conversion of the limiting reactant is analyzed in detail. The kinetics of silver nanoparticle synthesis using citrate reduction are investigated and used for development of a reaction engineering model to facilitate the reactor design. The effect of temperature, pH, concentration and mixing (axial dispersion) on the rates of nucleation and growth are analyzed quantitatively. An approach that considers reaction kinetics coupled with quality of dispersion is developed for reactor design as well as selection of reactor configurations for the synthesis of specific particle sizes. The developed approach has been applied for continuous production of 10-L suspension silver nanoparticles with very narrow particle size distribution.

Continuous Interfacial Centrifugal Separation and Recovery of Silver Nanoparticles

“…As such, the addition of PVP is also an important part of process development towards the production of AgNP powder. The process for synthesis of citrate‐capped AgNPs on large scale in continuous flow is reported elsewhere indicating that PVP needed to be added to high concentrations (13 %) to effectively cap the citrate‐stabilized AgNPs.…”

Importance of Monitoring the Synthesis of Light‐Interacting Nanoparticles – A Review on In Situ, Ex Situ, and Online Time‐Resolved Studies

“…For this, it is important to ensure that the microreactor design promotes mixing, leading to very low initial measurement times (typically in the range of milliseconds), to the point of being negligible in comparison to the early stage synthetic reaction times. [ 200,293 ] If this is not the case, the kinetic data are inaccurate until the initial measurement residence time is achieved. To tackle this issue, Epps et al.…”

Kinetics-based design of a flow platform for highly reproducible on demand synthesis of gold nanoparticles with controlled size between 50 and 150 nm and their application in SERS and PIERS sensing

“…Deshpande and Kulkarni [24] reported the synthesis of silver nanoparticles in size range between 65 and 120 nm using a cascade of CSTRs, however producing particles with broad size distribution. More recently, Pinho and Torrente-Murciano [25] reported the synthesis of silver nanoparticles with average size between 5 and 80 nm in a millifluidic reactor.…”