Raven's Coloured Progressive Matrices as a measure of cognitive functioning in Cerebral Palsy

Pueyo, Roser; Junqué, Carme; Vendrell, Pere; Narberhaus, Ana; Segarra, Dolors

doi:10.1111/j.1365-2788.2008.01045.x

Cited by 53 publications

(43 citation statements)

References 42 publications

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“…A cutoff of 1.5 SD was chosen to apply a consistent scale for all 6 assessments, which in previously published works have had clinical disability defined at various levels including 1, 1.5, or 2 SD from the mean. [32][33][34][35][36] We set the a priori P value to P , .05. For the t tests and x 2 tests, corrections for multiple comparisons were made by using the Holm-Bonferroni method.…”

Section: Discussionmentioning

confidence: 99%

Long-term Differences in Language and Cognitive Function After Childhood Exposure to Anesthesia

Ing¹,

DiMaggio

Whitehouse³

et al. 2012

Pediatrics

560

408

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BACKGROUND: Over the past decade, the safety of anesthetic agents in children has been questioned after the discovery that immature animals exposed to anesthesia display apoptotic neurodegeneration and long-term cognitive deficiencies. We examined the association between exposure to anesthesia in children under age 3 and outcomes in language, cognitive function, motor skills, and behavior at age 10. METHODS: We performed an analysis of the Western Australian Pregnancy Cohort (Raine) Study, which includes 2868 children born from 1989 to 1992. Of 2608 children assessed, 321 were exposed to anesthesia before age 3, and 2287 were unexposed. RESULTS: On average, exposed children had lower scores than their unexposed peers in receptive and expressive language (Clinical Evaluation of Language Fundamentals: Receptive [CELF-R] and Expressive [CELF-E]) and cognition (Colored Progressive Matrices [CPM]). After adjustment for demographic characteristics, exposure to anesthesia was associated with increased risk of disability in language (CELF-R: adjusted risk ratio [aRR], 1.87; 95% confidence interval [CI], 1.20–2.93, CELF-E: aRR, 1.72; 95% CI, 1.12–2.64), and cognition (CPM: aRR, 1.69; 95% CI, 1.13–2.53). An increased aRR for disability in language and cognition persisted even with a single exposure to anesthesia (CELF-R aRR, 2.41; 95% CI, 1.40–4.17, and CPM aRR, 1.73; 95% CI, 1.04–2.88). CONCLUSIONS: Our results indicate that the association between anesthesia and neuropsychological outcome may be confined to specific domains. Children in our cohort exposed to anesthesia before age 3 had a higher relative risk of language and abstract reasoning deficits at age 10 than unexposed children.

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Section: Discussionmentioning

confidence: 99%

Long-term Differences in Language and Cognitive Function After Childhood Exposure to Anesthesia

Ing¹,

DiMaggio

Whitehouse³

et al. 2012

Pediatrics

560

408

View full text Add to dashboard Cite

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“…The subjects underwent neurological examinations, including UPDRS‐III and PSP Rating Scale (PSPRS), for assessing motor symptoms and psychological evaluation, including Mini‐Mental State Examination (MMSE), Clinical Dementia Rating Scale (CDR), and Wechsler Memory Scale Revised Logical Memory II (WMSR LM‐II), for assessing cognitive and functional impairment, Frontal Assessment Battery (FAB) for assessing frontal dysfunction, and Raven's Coloured Progressive Matrices (RCPM) for assessing nonverbal cognitive impairment. RCPM reflects receptive vocabulary and visuospatial measures, and it can reportedly be conducted for subjects with severe motor impairments . Clinical scores of PSPRS, FAB, CDR Sum of Boxes (CDR‐SOB), WMSR‐LM II, and RCPM were available in 10 (subcategory = 9), 12, 12, 9, and 11 PSP patients, respectively, and all scores except PSPRS were obtained from each of the HCs.…”

Section: Methodsmentioning

confidence: 99%

“…RCPM reflects receptive vocabulary and visuospatial measures, and it can reportedly be conducted for subjects with severe motor impairments. 21,22 Clinical scores of PSPRS, FAB, CDR Sum of Boxes (CDR-SOB), WMSR-LM II, and RCPM were available in 10 (subcategory = 9), 12, 12, 9, and 11 PSP patients, respectively, and all scores except PSPRS were obtained from each of the HCs. Subjects aged >60 years with CDR-SOB = 0 and WMSR LM-II percentile >40 were recruited as HCs.…”

Section: Subjectsmentioning

confidence: 99%

In vivo binding of a tau imaging probe, [¹¹C]PBB3, in patients with progressive supranuclear palsy

et al. 2019

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Background [ 11 C]pyridinyl‐butadienyl‐benzothiazole 3 is a PET imaging agent designed for capturing pathological tau aggregates in diverse neurodegenerative disorders, and would be of clinical utility for neuropathological investigations of PSP. Objectives To explore the usefulness of [ 11 C]pyridinyl‐butadienyl‐benzothiazole 3/PET in assessing characteristic distributions of tau pathologies and their association with clinical symptoms in the brains of living PSP patients. Methods We assessed 13 PSP patients and 13 age‐matched healthy control subjects. Individuals negative for amyloid β PET with [ 11 C]Pittsburgh compound B underwent clinical scoring, MR scans, and [ 11 C]pyridinyl‐butadienyl‐benzothiazole 3/PET. Results There were significant differences in binding potential for [ 11 C]pyridinyl‐butadienyl‐benzothiazole 3 between PSP patients and healthy control subjects ( P = 0.02). PSP patients exhibited greater radioligand retention than healthy control subjects in multiple brain regions, including frontoparietal white matter, parietal gray matter, globus pallidus, STN, red nucleus, and cerebellar dentate nucleus. [ 11 C]pyridinyl‐butadienyl‐benzothiazole 3 deposition in frontoparietal white matter, but not gray matter, was correlated with general severity of parkinsonian and PSP symptoms, whereas both gray matter and white matter [ 11 C]pyridinyl‐butadienyl‐benzothiazole 3 accumulations in the frontoparietal cortices were associated with nonverbal cognitive impairments. Autoradiographic and fluorescence labeling with pyridinyl‐butadienyl‐benzothiazole 3 was observed in gray matter and white matter of PSP motor cortex tissues. Conclusions Our findings support the in vivo detectability of tau fibrils characteristic of PSP by [ 11 C]pyridinyl‐butadienyl‐benzothiazole 3/PET, and imply distinct and synergistic contributions of gray matter and white matte tau pathologies to clinical symptoms. [ 11 C]pyridinyl‐butadienyl‐benzothiazole 3/PET potentially provides a neuroimaging‐based index for the evolution of PSP tau pathologies promoting the deterioration of motor and cognitive functions. © 2019 The Authors. Movement Disorders published by Wiley Periodicals, Inc. on behalf of International Parkinson and Movement Disorder Society.

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“…The patient's general cognitive level was assessed with the Raven's Coloured Progressive Matrices, CPM (Raven & Raven, 1986), which has been recently shown to be a valid tool in the assessment of cognitive functioning in CP (Barca, Pezzulo, et al, 2010;Pueyo, Junquè, Vendrell, Narberhaus, & Segarra, 2008a, 2008b. Test materials consist in visual patterns presented with increasing difficulty.…”

Section: Cognitive Levelmentioning

confidence: 99%

Working memory and mental imagery in Cerebral Palsy: A single case investigation

2012

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In this study we describe visuospatial working memory and visual mental imagery of a child with Cerebral Palsy. Beyond a moderate impairment of visuomotor integration skills, cognitive level and memory span, poor performance emerged in figures reconstruction, in memorizing matrix patterns and movements along a path. No such deficits were observed in recalling figures and their positions on a grid and learning groups of words using a visual imagery strategy. This case highlights that impaired action execution impairs performance in imagery tasks as well, but not when alternative strategies (e.g., verbal encoding) can be adopted. Results are discussed considering recent evidence on working memory and visual imagery links, and their role in motor rehabilitation training.

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Raven's Coloured Progressive Matrices as a measure of cognitive functioning in Cerebral Palsy

Abstract: Raven's Coloured Progressive Matrices is a fast, easy-to-administer test able to obtain a measure related with linguistic, visuoperceptual, and memory cognitive functioning in persons with CP despite their motor and speech disorders.

Cited by 53 publications

References 42 publications

Long-term Differences in Language and Cognitive Function After Childhood Exposure to Anesthesia

Long-term Differences in Language and Cognitive Function After Childhood Exposure to Anesthesia

In vivo binding of a tau imaging probe, [¹¹C]PBB3, in patients with progressive supranuclear palsy

Working memory and mental imagery in Cerebral Palsy: A single case investigation

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Raven's Coloured Progressive Matrices as a measure of cognitive functioning in Cerebral Palsy

Abstract: Raven's Coloured Progressive Matrices is a fast, easy-to-administer test able to obtain a measure related with linguistic, visuoperceptual, and memory cognitive functioning in persons with CP despite their motor and speech disorders.

Cited by 53 publications

References 42 publications

Long-term Differences in Language and Cognitive Function After Childhood Exposure to Anesthesia

Long-term Differences in Language and Cognitive Function After Childhood Exposure to Anesthesia

In vivo binding of a tau imaging probe, [11C]PBB3, in patients with progressive supranuclear palsy

Working memory and mental imagery in Cerebral Palsy: A single case investigation

Contact Info

Product

Resources

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In vivo binding of a tau imaging probe, [¹¹C]PBB3, in patients with progressive supranuclear palsy