Rationalisation of the sizes of small molecules in gel permeation chromatography

Abstract

Published data on the sizes of small molecules measured by gel permeation chromatography are reconsidered after subjecting them to a recalculation procedure which gives molecular sizes in consistent units. Almost half the results are rejected as being unreliable. A set of molar volume values for n‐alkanes is recommended as a standard which should be used to calibrate gel permeation chromatographs irrespective of operating conditions. Molar volumes of some simple gases are given.