“…On the other hand, 13 IS elements were found in the ATH-43 genome sequence using the IS finder tool (www-is.biotoul.fr), along with 21 transposases and 17 integrases (not shown), all elements routinely associated with horizontal gene transfer providing advantage in metal and antibiotic resistance, general stress tolerance, and aromatic compound degradation, among others (Vos et al, 2015; Koonin, 2016). As with tRNA genes, the genome of ATH-43 displays a higher number of genetic determinants involved in metal, antibiotic, and oxidative stress resistance as compared with other reference P. putida genomes (Wu et al, 2011), which may be a reflect of the dramatic selective pressure occurring in the Antarctic continent.…”