Rates of Asymptomatic Nonurethral Gonorrhea and Chlamydia in a Population of University Men Who Have Sex With Men

Pinsky, Laura; Chiarilli, Daniel B.; Klausner, Jeffrey D.; Kull, Ryan M.; O’Keefe, Richard A.; Heffer, Calley; Seward, Samuel L.

doi:10.1080/07448481.2012.690465

Cited by 26 publications

(21 citation statements)

References 21 publications

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“…18,19 The rates of rectal chlamydial infection in men who have sex with men (MSM) have been reported to be between 3% and 10.5% in some settings. 20,21 An 8.4% prevalence of anorectal C. trachomatis in women has been reported and almost all (94.5%) of these women also had urogenital C. trachomatis . 22,23 Pharyngeal chlamydial infections are also usually asymptomatic, but symptoms of a mild sore throat can occur.…”

Section: Clinical Features Complications and Sequelaementioning

confidence: 99%

2015 European guideline on the management of Chlamydia trachomatis infections

et al. 2015

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Chlamydia trachomatis infections, which most frequently are asymptomatic, are major public health concerns globally. The 2015 European C. trachomatis guideline provides: up-to-date guidance regarding broader indications for testing and treatment of C. trachomatis infections; a clearer recommendation of using exclusively-validated nucleic acid amplification tests for diagnosis; advice on (repeated) C. trachomatis testing; the recommendation of increased testing to reduce the incidence of pelvic inflammatory disease and prevent exposure to infection; and recommendations to identify, verify and report C. trachomatis variants. Improvement of access to testing, test performance, diagnostics, antimicrobial treatment and follow-up of C. trachomatis patients are crucial to control its spread. For detailed background, evidence base and discussions, see the background review for the present 2015 European guideline on the management of Chlamydia trachomatis infections (Lanjouw E, et al. Int J STD AIDS. 2015).

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Section: Clinical Features Complications and Sequelaementioning

confidence: 99%

2015 European guideline on the management of Chlamydia trachomatis infections

et al. 2015

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“…21,22 However, several obstacles impede implementation of these recommendations, including perceived or actual cost of testing, lack of test kit availability, and insufficient awareness of the need to screen asymptomatic individuals at all relevant anatomic sites. 21,23 These difficulties are likely to be of greater impact in settings such as Thailand, where HIV prevalence and incidence among MSM are high and where lack of epidemiological data and cost of testing may impede routine screening. 24,25 For example, in Chiang Mai, Thailand, during the course of STI screening for the Pre-Exposure Prophylaxis Initiative trial, only 4 cases of CT and NG infection were confirmed in 22 individuals, with STI symptoms consenting to evaluation, among 551 study volunteers.…”

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confidence: 99%

Prevalence and Correlates of Chlamydia trachomatis and Neisseria gonorrhoeae by Anatomic Site Among Urban Thai Men Who Have Sex With Men

Tongtoyai

Todd

Chonwattana

et al. 2015

Sexually Transmitted Diseases

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“…The laboratory system used unique test numbers to distinguish rectal, pharyngeal, and urethral or urine specimens. Because nucleic acid amplification tests (NAATs) have not been cleared by FDA for the detection of rectal and oropharyngeal GC and CT infection, the laboratory had previously validated testing of rectal and pharyngeal specimens with NAATs to report results for patient management [11,12]. In this analysis, tests on urogenital specimens ordered under this test code will be referred to as urine.…”

Section: Methodsmentioning

confidence: 99%

Rectal Infection WithNeisseria gonorrhoeaeandChlamydia trachomatisin Men in the United States

et al. 2016

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Background. Centers for Disease Control and Prevention guidelines recommend at least annual rectal screening of men who have receptive anal intercourse for Neisseria gonorrhoeae (GC) and Chlamydia trachomatis (CT). Only limited national data are available on the prevalence of rectal GC and CT infection among US men.Methods. In collaboration with a large US commercial laboratory, we estimated positivity of the first rectal GC and CT test ("index" test) in men aged 15-60 years tested between January 2013 and May 2015. We estimated the frequency and positivity of pharyngeal or urine specimens tested for GC and CT on the index date, and the frequency and positivity of repeat rectal testing or any follow-up testing at any anatomic site after the index date.Results. Of 52 063 tested men aged 15-60 years, approximately 6.1% were positive for GC only, 8.3% for CT only, and 2.7% for both GC and CT on their index date. On that date, 86.5% had either urine or pharyngeal specimens collected, and 56.1% had both specimens collected. Pharyngeal GC infection was highly associated with rectal GC infection. Follow-up testing after 12 months ranged from 42.4% among uninfected men to 56.7% among infected men on the index date. Positivity was at least 5.7% in rectal GC, rectal CT, or pharyngeal GC at their last test.Conclusions. This analysis of a large number of male rectal specimens tested for GC and CT suggest that routine testing and timely repeat rectal GC and CT testing should be prioritized among men who report receptive rectal sex.

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Rates of Asymptomatic Nonurethral Gonorrhea and Chlamydia in a Population of University Men Who Have Sex With Men

Cited by 26 publications

References 21 publications

2015 European guideline on the management of Chlamydia trachomatis infections

2015 European guideline on the management of Chlamydia trachomatis infections

Prevalence and Correlates of Chlamydia trachomatis and Neisseria gonorrhoeae by Anatomic Site Among Urban Thai Men Who Have Sex With Men

Rectal Infection WithNeisseria gonorrhoeaeandChlamydia trachomatisin Men in the United States

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