Rates and Predictors of Adherence with Atypical Antipsychotic Medication: AFollow-Up Study of Adolescent Inpatients

Pogge, David L.; Singer, Melissa Biren; Harvey, Philip D.

doi:10.1089/cap.2005.15.901

Cited by 50 publications

(61 citation statements)

References 28 publications

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“…Although the secondgeneration antipsychotics have a lesser propensity for extra-pyramidal side effects they are associated with metabolic disturbance and weight gain, to which adolescents may be more vulnerable than their adult counterparts (Stigler et al, 2004;Pogge et al, 2005). Other factors suggested to have been involved in increasing antipsychotic prescribing are the expanding evidence base in relation to antipsychotic use in this age group (Harrison et al, 2012) and a lack of availability of non-pharmacological treatments (Thomas et al, 2006).…”

Section: Introductionmentioning

confidence: 99%

Psychotropic prescribing patterns among adolescents in Northern Ireland presenting with psychotic symptoms during a 5-year period

Woods¹,

Shannon²,

Davidson³

et al. 2015

Ir. j. psychol. Med.

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Objective: to report new prescriptions of psychotropic medications among adolescents presenting with new onset psychotic symptoms during a five-year period. Results: A total of 100 patients (88.5%) were prescribed some form of psychotropic medication.Over three-quarters of patients received an antipsychotic as their first medication. Risperidone (45.8%), olanzapine (24.0%) and chlorpromazine (12.5%) were the most commonly prescribed first-line antipsychotic medications. Of a total of 160 antipsychotic prescriptions, 81 (50.6%) were off-label. Prescriptions were most likely to have been deemed off-label due to medications not being licensed in under-18s (71.6% of off-label prescriptions) but other reasons were medications being used outside licensed age ranges (23.5%) and outside licensed indications (4.9%).Conclusions: This is the first study examining psychotropic prescribing patterns in a complete sample of all children and adolescents presenting with early onset psychotic episodes in a single geographical area. The observation of risperidone as the most commonly-prescribed antipsychotic was in keeping with previous studies in child and adolescent populations. Rates of off-label prescribing were lower than previously observed although our study was the first to investigate offlabel prescribing solely in children and adolescents presenting with psychotic symptoms.2

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Section: Introductionmentioning

confidence: 99%

Psychotropic prescribing patterns among adolescents in Northern Ireland presenting with psychotic symptoms during a 5-year period

Woods¹,

Shannon²,

Davidson³

et al. 2015

Ir. j. psychol. Med.

View full text Add to dashboard Cite

show abstract

“…The majority of the studies (n = 13) examined adherence to medication (25)(26)(27)(28)(29)(30)(31)(32)(33)(34)(35)(36)(37), and one study dealt with treatment engagement (38). Three studies investigated the outcomes of treatment and adherence (39)(40)(41), and one study focused on adherence to therapy (32).…”

Section: Basic Characteristics Of the Studiesmentioning

confidence: 99%

Factors that Affect Adolescent Adherence to Mental Health and Psychiatric Treatment: a Systematic Integrative Review of the Literature

Timlin

Hakko

Heino

et al. 2014

Scandinavian Journal of Child and Adolescent Psychiatry and Psychology

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Background: Although adherence to somatic treatment has been studied extensively, adherence to mental health treatment has not. In this study, the term treatment adherence is used to refer to adherence to medication regimes and other non-pharmacological recommended treatments as part of mental health and psychiatric care. Knowledge of factors connected to adolescents' adherence to such treatment is fairly fragmented. Although treatment staff members are broadly aware of the factors that influence adherence, it would be desirable to develop formalized treatment assessment and planning approaches that specifically take these factors into account. Objective: The purpose of this article is to review the available data related to factors that affect adolescents' adherence to both medication and non-pharmacological treatments in mental health and psychiatric care. Methods: A systematic literature search that involved four databases was undertaken. A thematic analysis was conducted on 17 studies to extract relevant information. Results: It appears that an adolescent's own positive beliefs toward his or her treatment are the main factor that improves his or her adherence to that treatment. Good cohesion with close supportive people appears to be positively related to adherence, whereas sociodemographic characteristics (e.g., race, gender) were not related. Conclusions: By identifying the factors related to the treatment adherence of adolescents, this review article can provide guidance to help improve the quality of care and thus further increase adolescents' satisfaction with their mental health and psychiatric treatment.

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“…In terms of demographics, older age, male gender and ethnic minority status have been relatively consistently associated with poorer adherence [41,42,[46][47][48][49]. Nonadherence rates in pediatric psychiatry are either unassociated or inconsistently associated with specific diagnoses, severity of symptoms, and physical side effects [46,[50][51][52][53][54]. There is some evidence that youth with externalizing behavior problems are less likely to be adherent than peers with primarily internalizing problems [49,51,53,55].…”

Section: Youths' Adherence To Psychotropic Medication and Correlates mentioning

confidence: 99%

Adolescents’ Commitment to Continuing Psychotropic Medication: A Preliminary Investigation of Considerations, Contradictions, and Correlates

Moses

2010

Child Psychiatry Hum Dev

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This mixed-method study examines (1) the extent to which fifty adolescents receiving wraparound treatment and prescribed psychotropic medication for various psychiatric disorders report that they would continue taking medication if the decision was entirely their own (termed "medication commitment"); (2) their general subjective experiences with medication; and (3) which medication experiences and clinical, social, and demographic factors are associated with greater medication commitment. We found that most adolescents (62%) would discontinue treatment; these "less committed" youth were more likely to report various negative medication perceptions and experiences in open-ended questions, relative to "committed" youth. Multivariate analysis indicated that significant correlates of commitment to medication were: taking antipsychotic medication, greater perceived family support, and lack of perceived coercion to take the medication; clinical or demographic factors were not significantly related to medication commitment. The results reinforce the importance of addressing youths' concerns about medication and maximizing their participation in treatment decision-making.

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Rates and Predictors of Adherence with Atypical Antipsychotic Medication: AFollow-Up Study of Adolescent Inpatients

Cited by 50 publications

References 28 publications

Psychotropic prescribing patterns among adolescents in Northern Ireland presenting with psychotic symptoms during a 5-year period

Psychotropic prescribing patterns among adolescents in Northern Ireland presenting with psychotic symptoms during a 5-year period

Factors that Affect Adolescent Adherence to Mental Health and Psychiatric Treatment: a Systematic Integrative Review of the Literature

Adolescents’ Commitment to Continuing Psychotropic Medication: A Preliminary Investigation of Considerations, Contradictions, and Correlates

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