Rare metastasis of nasopharyngeal carcinoma to the thyroid gland with subsequent metastatic abdominal lymph nodes

Cai, Changjing; Shen, Hong; Liu, Wenqiang; Ma, Junli; Zhang, Yan; Yin, Ling; Li, Jindong; Shen, Liangfang; Zeng, Shan

doi:10.1097/md.0000000000008373

Cited by 3 publications

(2 citation statements)

References 5 publications

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“…Only B + FB metastases were found in this case, which is uncommon. The other uncommon sites of distant metastasis in NPC are the skin, 10 thyroid glands, 11 rectum, 12 and spleen. 13 A remarkable feature of our patient was the notably large bilateral cervical lymph nodes and advanced N classification (staged as N3).…”

Section: Discussionmentioning

confidence: 99%

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Brain and frontal‐bone metastasis from nasopharyngeal carcinoma: Case report and literature review

Cao

Zou

2019

Head & Neck

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Background Metastases to the bones, lungs, and liver are common in patients with nasopharyngeal carcinoma (NPC) but not to the brain and frontal bone (B + FB). Methods We describe a patient with NPC with B + FB metastasis. He received two cycles of palliative chemotherapy (gemcitabine and cisplatin) and then radiotherapy (60 Gy) for B + FB metastasis. A literature review of previous cases was also undertaken. Results Follow‐up 6 months after completion of chemotherapy and radiotherapy showed that our patient experienced a complete response without signs of NPC progression. Conclusions B + FB metastases from NPC are uncommon. Our case highlights the diagnostic and treatment difficulties clinicians face when dealing with patients with uncommon sites of metastasis. Optimal adjuvant therapy followed by local radiotherapy might elicit long survival in patients with NPC with uncommon sites of metastasis.

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Section: Discussionmentioning

confidence: 99%

“…Only B + FB metastases were found in this case, which is uncommon. The other uncommon sites of distant metastasis in NPC are the skin, thyroid glands, rectum, and spleen …”

Section: Discussionmentioning

confidence: 99%

Brain and frontal‐bone metastasis from nasopharyngeal carcinoma: Case report and literature review

Cao

Zou

2019

Head & Neck

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Prevalencia de tumores metastásicos en la glándula tiroides. Revisión sistemática y metanálisis.

Rodrigo-Gómez

Pardal-Refoyo

Batuecas‐Caletrío

2020

ORL

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Fecha de publicación del fascículo: pendiente de publicación Conflicto de intereses: Los autores declaran no tener conflictos de intereses Imágenes: Los autores declaran haber obtenido las imágenes con el permiso de los pacientes Política de derechos y autoarchivo: se permite el autoarchivo de la versión post-print (SHERPA/RoMEO) Licencia CC BY-NC-ND. Licencia Creative Commons Atribución-NoComercial-SinDerivar 4.0 Internacional Universidad de Salamanca. Su comercialización está sujeta al permiso del editor Ediciones Universidad de Salamanca / CC BY-NC-ND [2] Rev. ORL, 20xx, x, x, pp. xx-xx Conclusiones: La prevalencia de metástasis en tiroides es superior en las series de autopsias que en series clínicas (hasta 6.67 veces más frecuente en nuestro estudio). Las metástasis intratiroideas probablemente están infradiagnosticadas por cursar sin clínica siendo diagnosticadas como hallazgo casual en autopsias. Los tumores primarios más frecuentes fueron el riñón (series clínicas) y la mama (series de autopsias). PALABRAS CLAVE metástasis en tiroides; metástasis intratiroideas; prevalencia; neoplasia secundaria de tiroides; revisión; metanálisis

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Thyroid metastatic carcinoma caused by primary lung cancer—a case report

Zhang¹,

Zhao²,

Chong³

et al. 2021

Ann Palliat Med

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Thyroid metastatic cancer is rare. It may be ignored due to the longer course of the primary disease and the less obvious symptoms. With the popularity of ultrasonography, it can help the early detection of thyroid metastatic cancer. In this case, a 50-year-old woman was diagnosed with thyroid metastasis due to a "decade of lung cancer". The main clinical manifestation of the patient was that although the thyroid area was not enlarged, the texture was stiff. Unlike common thyroid cancer, this patient did not experience hoarseness. The patient underwent ultrasound-guided biopsy of the thyroid area and examined the pathological section. Unlike previous ultrasound manifestations of common thyroid metastatic cancer, the ultrasound results in this case were shown as diffuse, point-like hyperechoic. Ultrasound-guided biopsy of the thyroid site was performed on the patient, and pathological sections were examined. The obtained thyroid pathology section results are shown that metastases of poorly differentiated cancers, tending to adenocarcinoma, considering metastasis in combination with history. The treatment used by this patient was taking thyroxine tablets, but the efficacy was not satisfactory. Early diagnosis of metastatic cancer provides feasible help, and ultrasound-guided puncture biopsy may be used to further diagnose metastatic thyroid cancer if necessary.

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Rare metastasis of nasopharyngeal carcinoma to the thyroid gland with subsequent metastatic abdominal lymph nodes

Cited by 3 publications

References 5 publications

Brain and frontal‐bone metastasis from nasopharyngeal carcinoma: Case report and literature review

Brain and frontal‐bone metastasis from nasopharyngeal carcinoma: Case report and literature review

Prevalencia de tumores metastásicos en la glándula tiroides. Revisión sistemática y metanálisis.

Thyroid metastatic carcinoma caused by primary lung cancer—a case report

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