“…It plays a crucial role in controlling the dormancy of disseminated cancer cells, since immune suppression also accelerates the development of metastases. While pregnancy does not increase the risk of melanoma (Lens and Bataille, 2008), it may accelerate the development of metastatic disease (Sato et al, 2008;Youn et al, 2010). We also showed that RETAAD mice depleted of CD8 + T cells develop visceral metastases much earlier than control mice (Eyles et al, 2010;Lengagne et al, 2008).…”