Rapid naked-eye detection of mercury ions based on non-crosslinking aggregation of double-stranded DNA-carrying gold nanoparticles

Abstract

Colorimetric detection of mercury ions (Hg(2+)) with the naked eye was accomplished within 1 min by a combination of non-crosslinking aggregation of double-stranded DNA-carrying gold nanoparticles and complex formation of thymine-Hg(2+)-thymine.

Colorimetric detection of lead (II) based on silver nanoparticles capped with iminodiacetic acid

“…Huang and his group reported polythyminestabilized gold nanoparticles for the recognition of melamine [23]. Takarda and his group developed doublestranded DNA-carrying gold nanoparticles for detection of mercury ion [24]. Recently, Chai and his group [9] have reported glutathione modified gold nanoparticles based colorimetric assay for the detection of Pb 2+ at 20 ppb level.…”

Metal-Mediated Base Pairs in Nucleic Acids with Purine- and Pyrimidine-Derived Nucleosides

“…Originally proposed to explain changes in the physical properties of natural DNA that was observed in the presence of certain transition metal ions, they are nowadays discussed and utilized in the context of sophisticated DNA-based applications such as metal ion sensors [ 71,72 ] , sensors for the redox environment [ 41 ] , molecular logic gates [ 70 ] , the detection of single nucleotide polymorphisms [ 73 ] , long-distance charge transfer [ 74 ] , and DNA-based machines like bipedal walkers and steppers [ 75 ] . This wealth of possible applications will undoubtedly increase even further with the development of new metal-mediated base pairs including entirely artifi cial nucleosides [ 12 ] .…”

An electrochemical aptamer biosensor based on “gate-controlled” effect using β-cyclodextrin for ultra-sensitive detection of trace mercury

“…Thus, developing sensitive and selective methods for detecting heavy metal ions is of crucial significance. Although a number of analytical methods for Hg 2 þ analysis have been developed and several sensors employing colorimetry (Li et al, 2009b;Xue et al,2008;He et al, 2008;Liu et al, 2010;Kanayama et al, 2011;Lee et al, 2007), fluorescence (Ando and Koide, 2011;Yang et al, 2009;Freeman et al, 2009), QD-fluorescence (Paramanik et al, 2013), SPR (Yu et al, 2004), SERS (Wang and Chen, 2009) and electrochemistry (Cao et al, 2009;Liu et al, 2009;Zhu et al, 2009) have been proposed, the detection limits of these methods and electrodes are not sufficiently low. As such, developing a method that is highly sensitive and analytical is an urgent necessity.…”