Rapid loading of sotalol or amiodarone for management of recent onset symptomatic atrial fibrillation: a randomized, digoxin-controlled trial

Part 8: Adult Advanced Cardiovascular Life Support

“…IV ␤-blockers and nondihydropyridine calcium channel blockers such as diltiazem 430 -433 are the drugs of choice for acute rate control in most individuals with atrial fibrillation and rapid ventricular response (Class IIa, LOE A). Digoxin 434 -436 and amiodarone 437,438 may be used for rate control in patients with congestive heart failure; however, the potential risk of conversion to sinus rhythm with amiodarone should be considered before treating with this agent.…”

2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS

“…Leki antyarytmiczne mogą przywracać rytm zatokowy u pacjentów z AF (kardiowersja farmakologiczna), co wykazano w małych kontrolowanych próbach klinicznych, metaanalizach [41,584,595,596] oraz niewielu większych kontrolowanych próbach klinicznych [597][598][599][600][601][602][603][604][605]. Poza Europą jest dostępny dofetilid, który może przerwać AF o niedawnym początku [606].…”

Part 8: Advanced Life Support

“…323,326 Sotalol has consistently been shown to be inferior in conversion compared to other drugs (LOE 1: flecainide 318 and ibutalide 308 ), but equal to amiodarone in 1 study (LOE 1). 325 Most studies showed no conversion benefit for magnesium (LOE 1), 327,328 although 1 meta-analysis showed conversion benefit (LOE 1).…”