Rapid determination of tricaine mesylate residues in fish samples using modified QuEChERS and high-performance liquid chromatography-tandem mass spectrometry

Li, Jincheng; Liu, Huan; Yu, Man; Wu, Lidong; Wang, Qun; Lv, Haiyan; Ma, Bing; Song, Yi

doi:10.1039/c4ay00784k

Cited by 21 publications

(23 citation statements)

References 17 publications

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“…The exposure study was performed by short-term exposure to eugenol solution following the method described in our previous work [3]. Exposure baths were prepared in aquariums (160×60×80 cm, length×width×depth) which were filled with 10.0 mg L −1 eugenol solution.…”

Section: Fish-exposure Experimentsmentioning

confidence: 99%

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Optimization of solid-phase-extraction cleanup and validation of quantitative determination of eugenol in fish samples by gas chromatography–tandem mass spectrometry

Zhang

Liu

2015

Anal Bioanal Chem

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This paper describes a rapid and sensitive method for the determination of eugenol in fish samples, based on solid-phase extraction (SPE) and gas chromatography-tandem mass spectrometry (GC-MS-MS). Samples were extracted with acetonitrile, and then cleanup was performed using C18 solid-phase extraction (SPE). The determination of eugenol was achieved using an electron-ionization source (EI) in multiple-reaction-monitoring (MRM) mode. Under optimized conditions, the average recoveries of eugenol were in the range 94.85-103.61 % and the relative standard deviation (RSD) was lower than 12.0 %. The limit of detection (LOD) was 2.5 μg kg(-1) and the limit of quantification (LOQ) was 5.0 μg kg(-1). This method was applied to an exposure study of eugenol residue in carp muscle tissues. The results revealed that eugenol was nearly totally eliminated within 96 h. Graphical Abstract Flow diagram for sample pretreatment.

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Section: Fish-exposure Experimentsmentioning

confidence: 99%

“…Partial or whole-body anesthetic can be used on fish; after the use of anesthetic, the affected area will temporarily lose the feeling of pain and stress reaction will be reduced. Anesthetic has been widely used on fish in contexts including surgery, breeding, transport, and slaughter [2,3].…”

Section: Introductionmentioning

confidence: 99%

Optimization of solid-phase-extraction cleanup and validation of quantitative determination of eugenol in fish samples by gas chromatography–tandem mass spectrometry

Zhang

Liu

2015

Anal Bioanal Chem

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“…Sample preparation was carried out referring to our previous work (Li et al, 2014a(Li et al, , 2016. Muscle tissues were collected and homogenized.…”

Section: Sample Preparationmentioning

confidence: 99%

A novelty strategy for the fast analysis of sulfonamide antibiotics in fish tissue using magnetic separation with high‐performance liquid chromatography–tandem mass spectrometry

Liu

Zhang

et al. 2016

Biomedical Chromatography

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A simple, fast and low-cost extraction method with high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) determination was developed on sulfonamide antibiotics (SAs) in fish tissue. Magnetic separation was first introduced into the rapid sample preparation procedure combined with acetonitrile extraction for the analysis of SAs. Partitioning was rapidly achieved between acetonitrile solution and solid matrix by applying an external magnetic field. Acetonitrile solution was collected and concentrated under a nitrogen stream. The residue was redissolved with 1‰ formic acid aqueous solution and defatted with n-hexane before analysis. The recoveries of SAs were in the range of 74.87-104.74%, with relative standard deviations <13%. The limits of quantification and the limits of detection for SAs ranged from 5.0 to 25.0 μg (kg-1) and from 2.5 to 10.0 μg (kg-1) , respectively. The presented extraction method proved to be a rapid method which only took 20 min for one sample preparation procedure. Copyright © 2016 John Wiley & Sons, Ltd.

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“…Li et al. developed a modified QuEChERS method for the rapid determination of MS‐222 residues in fish samples with 300 mg PSA as dispersive solid‐phase extraction (d‐SPE) absorbents using LC–MS/MS.…”

Section: Introductionmentioning

confidence: 99%

Comparison of pulse glow discharge‐ion mobility spectrometry and liquid chromatography with tandem mass spectrometry based on multiplug filtration cleanup for the analysis of tricaine mesylate residues in fish and water

Zou

Chen

Qin

et al. 2016

J of Separation Science

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Analytical methods based on multiplug filtration cleanup coupled with pulse glow discharge-ion mobility spectrometry and liquid chromatography tandem mass spectrometry were developed for the analysis of tricaine mesylate residue in fish and fish-raising water samples. A silica fiber holder and an appropriate new interface were designed to make the direct introduction of the fiber into the pulse glow discharge-ion mobility spectrometry introduction mechanism. The multiplug filtration cleanup method with adsorption mixtures was optimized for the determination of tricaine mesylate in fish samples. Good linear relationships were obtained by the two methods. For fish samples, limits of detection were 6 and 0.6 μg/kg by ion mobility spectrometry and liquid chromatography with tandem mass spectrometry, respectively. The matrix effect of the established liquid chromatography tandem mass spectrometry method was negligible for fish samples but that of the ion mobility spectrometry method was not. The two methods were compared. The ion mobility spectrometry system could be used a rapid screening tool on site with the advantage of rapidity, simplicity, and portability, and the liquid chromatography tandem mass spectrometry system could be used for validation in laboratory conditions with the advantage of lower limit of detection, stability, and precision.

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Rapid determination of tricaine mesylate residues in fish samples using modified QuEChERS and high-performance liquid chromatography-tandem mass spectrometry

Abstract: A rapid and effective modified, quick, easy, cheap, effective, rugged, and safe (QuEChERS) method was developed for the determination of tricaine mesylate (MS-222) in fish samples using HPLC-MS/MS.

Cited by 21 publications

References 17 publications

Optimization of solid-phase-extraction cleanup and validation of quantitative determination of eugenol in fish samples by gas chromatography–tandem mass spectrometry

Optimization of solid-phase-extraction cleanup and validation of quantitative determination of eugenol in fish samples by gas chromatography–tandem mass spectrometry

A novelty strategy for the fast analysis of sulfonamide antibiotics in fish tissue using magnetic separation with high‐performance liquid chromatography–tandem mass spectrometry

Comparison of pulse glow discharge‐ion mobility spectrometry and liquid chromatography with tandem mass spectrometry based on multiplug filtration cleanup for the analysis of tricaine mesylate residues in fish and water

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