Rapid determination of trace amounts of minoxidil in hamster skin follicles with various formulations using narrow-bore LC/EC

Huang, Tian-Sen; Garceau, Michelle E.; Ramstad, Tore; Stehle, Randall G.

doi:10.1016/j.jpba.2005.01.032

Cited by 8 publications

(6 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Z uwagi na dyskomfort niektórych pacjentów stosujących roztwór, którego nośnik składa się z wody, alkoholu i glikolu propylenowego, opracowano preparat piankowy z minoksydylem, który nie zawiera glikolu propylenowego. W badaniach przeprowadzonych na zwierzętach preparat w postaci pianki okazał się równie skuteczny, jak minoksydyl w postaci roztworu [23]. Działania niepożądane w postaci świądu, w przypadku zastosowania 5% preparatu piankowego minoksydylu występowały u 1,1% badanych zwierząt, natomiast po zastosowaniu 5% roztworu minoksydylu u 6%.…”

Section: Opis Stanu Wiedzyunclassified

Pharmacotherapy of androgenetic alopecia – a literature review

Marcin

Pożarowska²,

Rosińska³

et al. 2022

J Educ Health Sport

View full text Add to dashboard Cite

INTRODUCTION: Androgenetic alopecia, also known as male pattern baldness, is a common dermatological problem. It manifests as hair thinning and miniaturization of hair follicles. In recent years, knowledge of the risk factors and pathomechanisms of this disease has increased, making treatment more effective. Serious consequences of this condition include reduced quality of life and patient self-esteem. PURPOSE OF THE WORK: The purpose of this paper is to review and discuss selected studies involving agents used in the pharmacotherapy of androgenetic alopecia and to evaluate their safety and efficacy. DESCRIPTION OF THE STATE OF KNOWLEDGE: There are two drugs approved by the Food and Drug Administration (FDA) for the treatment of androgenetic alopecia - oral finasteride 1 mg and 2% or 5% minoxidil solution for topical use. There are also other preparations for external use, such as 0.1% finasteride solution or ketoconaloze shampoo, and for oral use, dutasteride. They seem to be a promising alternative for the treatment of androgenetic alopecia, but require further research. It is possible to use one drug of choice or to use combination therapy to achieve better therapeutic effects. SUMMARY: In order to achieve the best and fastest treatment results, patients should be treated with combination therapy consisting of two or more preparations. To reduce systemic side effects, consider using several topical preparations.

show abstract

Section: Opis Stanu Wiedzyunclassified

Pharmacotherapy of androgenetic alopecia – a literature review

Marcin

Pożarowska²,

Rosińska³

et al. 2022

J Educ Health Sport

View full text Add to dashboard Cite

show abstract

“…A derivative of PPO that contained a polymerizable vinyl group, 2,5-diphenyl-4-(4 -vinylbenzyl) oxazole (PPOstyrene) was prepared by Stille coupling by making slight modifications to a previously reported reaction and purification method [13][14][15]. The structure of the product was confirmed using 1 H NMR (200 MHz, CDCl 3 ) and mass spectrometry (EI). This PPO-styrene monomer (3.13 mg ml −1 ) and bis-MSB (0.27 mg ml −1 ) were dissolved in styrene/DVB to form a microemulsion in SDS/H 2 O and subsequently subjected to thermally initiated radical polymerization.…”

Section: Preparation Of Nanosuspensions Using a Polymerizable Scintil...mentioning

confidence: 99%

“…The utility of radioisotopes in biomedical, pharmaceutical and environmental research stems from their chemical identity with their non-radioactive counterparts [1][2][3][4]. This allows their incorporation into 'tracers', radiolabelled components that can be followed and detected through a series of reaction steps and biological processes.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Aqueous polystyrene–fluor nanosuspensions for quantifying α and β⁻radiation

Zhu¹,

Jay²

2007

Nanotechnology

View full text Add to dashboard Cite

Fluor-containing nanoparticle suspensions prepared from styrene-in-water microemulsions were used to quantify 14C in various sample matrices by aqueous liquid scintillation counting. These suspensions exhibited greater quench resistance than a conventional organic cocktail and were very efficient at detecting higher energy β− emitters and α emitters. A polymerizable scintillant was prepared to prevent leaching of fluors. The relationship between particle size, kinetic energy of β− particles and counting efficiency was simulated by a theoretical model.

show abstract

“…[7] In an animal study, the foam formulation was found as effective as the liquid formulation. [8] It is a fact that the stratum corneum functions as a barrier for skin absorption and abraded or eczematized skin is a weak skin barrier, which leads to enhanced absorption of topical medications. In a study conducted by Wester et al ., 5% topical liquid form of minoxidil was observed to cause the greatest increase in the cutaneous blood flow by using Doppler velocimetry and photopulse plethysmography comparing to 1% and 3% topical liquid form of minoxidil.…”

mentioning

confidence: 99%